Jean-Paul Briand
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Explore the profile of Jean-Paul Briand including associated specialties, affiliations and a list of published articles.
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86
Citations
2290
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Recent Articles
1.
Wang F, Bonam S, Schall N, Kuhn L, Hammann P, Chaloin O, et al.
Sci Rep
. 2018 Nov;
8(1):16820.
PMID: 30429537
The nuclear translocation of endogenous heat shock cognate protein HSPA8 is a requisite for cell survival during oxidative and heat shock stress. Upon these events, cytoplasmic HSPA8 is thought to...
2.
Dieker J, Berden J, Bakker M, Briand J, Muller S, Voll R, et al.
PLoS One
. 2016 Oct;
11(10):e0165373.
PMID: 27780265
Persistent exposure of the immune system to death cell debris leads to autoantibodies against chromatin in patients with systemic lupus erythematosus (SLE). Deposition of anti-chromatin/chromatin complexes can instigate inflammation in...
3.
Macri C, Wang F, Tasset I, Schall N, Page N, Briand J, et al.
Autophagy
. 2015 Feb;
11(3):472-86.
PMID: 25719862
The P140 peptide, a 21-mer linear peptide (sequence 131-151) generated from the spliceosomal SNRNP70/U1-70K protein, contains a phosphoserine residue at position 140. It significantly ameliorates clinical manifestations in autoimmune patients...
4.
Dwivedi N, Neeli I, Schall N, Wan H, Desiderio D, Csernok E, et al.
FASEB J
. 2014 Mar;
28(7):2840-51.
PMID: 24671707
Autoantibodies to nuclear antigens arise in human autoimmune diseases, but a unifying pathogenetic mechanism remains elusive. Recently we reported that exposure of neutrophils to inflammatory conditions induces the citrullination of...
5.
Briand J, Schall N, Muller S
Methods Mol Biol
. 2014 Feb;
1134:173-92.
PMID: 24497362
Synthetic peptides are attracting increasing attention as therapeutics. Despite their potential, however, only a few selected peptides have been able to enter in clinical trials for chronic autoimmune diseases and...
6.
Destouches D, Huet E, Sader M, Frechault S, Carpentier G, Ayoul F, et al.
J Biol Chem
. 2012 Oct;
287(52):43685-93.
PMID: 23109338
Blockage of the metastasis process remains a significant clinical challenge, requiring innovative therapeutic approaches. For this purpose, molecules that inhibit matrix metalloproteinases activity or induce the expression of their natural...
7.
Schall N, Page N, Macri C, Chaloin O, Briand J, Muller S
J Autoimmun
. 2012 Jun;
39(3):143-53.
PMID: 22727561
After a long period where the potential of therapeutic peptides was let into oblivion and even dismissed, there is a revival of interest in peptides as potential drug candidates. Novel...
8.
Luce S, Lemonnier F, Briand J, Coste J, Lahlou N, Muller S, et al.
Diabetes
. 2011 Oct;
60(12):3289-99.
PMID: 21998398
Objective: Both the early steps and the high recurrence of autoimmunity once the disease is established are unexplained in human type 1 diabetes. Because CD8(+) T cells are central and...
9.
Page N, Gros F, Schall N, Briand J, Muller S
Autophagy
. 2011 Feb;
7(5):539-40.
PMID: 21282971
The P140 phosphopeptide encompassing residues 131-151 of the spliceosomal U1-70K snRNP protein displays protective properties in lupus patients and MRL/lpr mice. It increases peripheral blood lymphocyte apoptosis via a mechanism...
10.
Page N, Gros F, Schall N, Decossas M, Bagnard D, Briand J, et al.
Ann Rheum Dis
. 2010 Dec;
70(5):837-43.
PMID: 21173017
Background: The P140 phosphopeptide issued from the spliceosomal U1-70K small nuclear ribonucleoprotein protein displays protective properties in MRL/lpr lupus-prone mice. It binds both major histocompatibility class II (MHCII) and HSC70/Hsp73...