Jean-Michel Mesnard
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Explore the profile of Jean-Michel Mesnard including associated specialties, affiliations and a list of published articles.
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55
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2050
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Recent Articles
1.
Tram J, Marty L, Mourouvin C, Abrantes M, Jaafari I, Cesaire R, et al.
Cells
. 2024 Sep;
13(18.
PMID: 39329701
Human endogenous retroviruses (HERVs) are retroviral sequences integrated into 8% of the human genome resulting from ancient exogenous retroviral infections. Unlike endogenous retroviruses of other mammalian species, HERVs are mostly...
2.
Schatz M, Marty L, Ounadjela C, Tong P, Cardace I, Mettling C, et al.
J Virol
. 2023 May;
97(4):e0027823.
PMID: 37129415
HIV-1 Tat is a key viral protein that stimulates several steps of viral gene expression. Tat is especially required for the transcription of viral genes. Nevertheless, it is still not...
3.
Liu Z, Larocque E, Xie Y, Xiao Y, Lemay G, Peloponese J, et al.
Front Microbiol
. 2022 Dec;
13:988944.
PMID: 36532440
Human T-cell leukemia virus type 1 is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia-lymphoma (ATL). The HTLV-1 basic leucine zipper factor (HBZ) has been associated...
4.
Tram J, Mesnard J, Peloponese Jr J
Front Immunol
. 2022 Aug;
13:959382.
PMID: 35979354
Eukaryotic cells employ a broad range of mechanisms to regulate gene expression. Among others, mRNA alternative splicing is a key process. It consists of introns removal from an immature mRNA...
5.
Miller R, Zimmer A, Moutot G, Mesnard J, Chazal N
Viruses
. 2021 Nov;
13(11).
PMID: 34835027
Paradigm shifts throughout the history of microbiology have typically been ignored, or met with skepticism and resistance, by the scientific community. This has been especially true in the field of...
6.
Savoret J, Mesnard J, Gross A, Chazal N
Front Microbiol
. 2021 Jan;
11:625941.
PMID: 33510738
It was first predicted in 1988 that there may be an Open Reading Frame (ORF) on the negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could...
7.
Cate C, Larocque E, Peloponese J, Mesnard J, Rassart E, Barbeau B
Virologie (Montrouge)
. 2020 Oct;
22(3):183-191.
PMID: 33111675
There are four human T-lymphotropic viruses (HTLV-1, 2, 3, 4) that have emerged from the transmission of simian viruses. HTLV-1 was the first retrovirus to be shown to be responsible...
8.
A Pilot Study of the Humoral Response Against the AntiSense Protein (ASP) in HIV-1-Infected Patients
Savoret J, Chazal N, Moles J, Tuaillon E, Boufassa F, Meyer L, et al.
Front Microbiol
. 2020 Mar;
11:20.
PMID: 32117090
The existence of an antisense Open Reading Frame (ORF) that encodes a putative AntiSense Protein (ASP) on the proviral genome of Human Immunodeficiency Virus type 1 (HIV-1) was a source...
9.
Matsuoka M, Mesnard J
Retrovirology
. 2020 Jan;
17(1):2.
PMID: 31915026
Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in HTLV-1 infected cells and...
10.
Chopard C, Tong P, Toth P, Schatz M, Yezid H, Debaisieux S, et al.
Nat Commun
. 2018 Jun;
9(1):2251.
PMID: 29884859
Most HIV-1 Tat is unconventionally secreted by infected cells following Tat interaction with phosphatidylinositol (4,5) bisphosphate (PI(4,5)P) at the plasma membrane. Extracellular Tat is endocytosed by uninfected cells before escaping...