Jayaraj Ravindran
Overview
Explore the profile of Jayaraj Ravindran including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
981
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0
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Recent Articles
1.
Sung B, Ravindran J, Prasad S, Pandey M, Aggarwal B
J Biol Chem
. 2016 Aug;
291(32):16923.
PMID: 27496964
No abstract available.
2.
Sung B, Prasad S, Ravindran J, Yadav V, Aggarwal B
Free Radic Biol Med
. 2012 Aug;
53(10):1977-87.
PMID: 22922338
A major problem in clinical trials of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as cancer therapy is the development of resistance to TRAIL. Therefore, agents that can overcome TRAIL resistance...
3.
Kunnumakkara A, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, et al.
Int J Cancer
. 2011 Sep;
131(3):E292-303.
PMID: 21935918
Agents that can potentiate the efficacy of standard chemotherapy against pancreatic cancer are of great interest. Because of their low cost and safety, patients commonly use a variety of dietary...
4.
Sehgal P, Kumar O, Kameswararao M, Ravindran J, Khan M, Sharma S, et al.
Toxicology
. 2011 Jan;
282(1-2):56-67.
PMID: 21255629
Ricin is one of the most potent and deadly plant toxins from the seeds of Ricinus communis. In view of its high toxicity, ricin is being used as an immunotoxin...
5.
Prasad S, Yadav V, Ravindran J, Aggarwal B
Cancer Res
. 2010 Dec;
71(2):538-49.
PMID: 21127198
Because tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells, it is being tested in cancer patients. Unfortunately, patients develop resistance to the cytokine, therefore, agents that can...
6.
Ravindran J, Agrawal M, Gupta N, Lakshmana Rao P
Toxicology
. 2010 Nov;
280(1-2):44-52.
PMID: 21112371
T-2 toxin is a cytotoxic fungal secondary metabolite produced by different species of Fusarium such as F. sporotichioides, F. poae, F. equiseti, F. acuminatum etc. This class of mycotoxins causes...
7.
Ravindran J, Gupta N, Agrawal M, Bhaskar A, Lakshmana Rao P
Apoptosis
. 2010 Nov;
16(2):145-61.
PMID: 21082355
Okadaic acid (OA) is a specific and potent protein phosphatase inhibitor and tumor promoter. The present study establishes the role of reactive oxygen species (ROS) and mitogen activated protein kinases...
8.
Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav V, et al.
Cancer Prev Res (Phila)
. 2010 Oct;
3(11):1462-72.
PMID: 20978115
The discovery of new uses for older, clinically approved drugs is one way to expedite drug development for cancer. Thiocolchicoside, a semisynthetic colchicoside from the plant Gloriosa superba, is a...
9.
Kunnumakkara A, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, et al.
Cancer Res
. 2010 Sep;
70(21):8695-705.
PMID: 20864511
Pancreatic cancers generally respond poorly to chemotherapy, prompting a need to identify agents that could sensitize tumors to treatment. In this study, we investigated the response of human pancreatic cells...
10.
Sung B, Ravindran J, Prasad S, Pandey M, Aggarwal B
J Biol Chem
. 2010 Sep;
285(46):35418-27.
PMID: 20837473
Development of resistance to TRAIL, an apoptosis-inducing cytokine, is one of the major problems in its development for cancer treatment. Thus, pharmacological agents that are safe and can sensitize the...