Jayakrishna Ambati
Overview
Explore the profile of Jayakrishna Ambati including associated specialties, affiliations and a list of published articles.
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Articles
107
Citations
6679
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Recent Articles
1.
Li J, Nagasaka Y, Shen H, Zhou X, Ma J, Trevisan-Silva D, et al.
Mol Ther Nucleic Acids
. 2025 Feb;
36(1):102460.
PMID: 39995975
Epithelial-mesenchymal transition (EMT) is associated with retinal pigment epithelium (RPE) dysfunction in degenerative retinal diseases. However, the role of partial EMT (pEMT), a hybrid state exhibiting both epithelial and mesenchymal...
2.
Magagnoli J, Cummings T, Hardin J, Ambati J, Sutton S
Diabetes Obes Metab
. 2024 Nov;
27(2):675-682.
PMID: 39529444
Background: Chronic inflammation is a key factor in type 2 diabetes mellitus (T2DM) development. The cholinergic anti-inflammatory pathway (CAP) reduces inflammation by activating α7 nicotinic acetylcholine receptors (α7nAChRs) on macrophages,...
3.
Makin R, Apicella I, Dholkawala R, Fukuda S, Hirahara S, Hirano Y, et al.
Angiogenesis
. 2024 Sep;
27(4):919-929.
PMID: 39316206
Inflammasome activation is implicated in diseases of aberrant angiogenesis such as age-related macular degeneration (AMD), though its precise role in choroidal neovascularization (CNV), a characteristic pathology of advanced AMD, is...
4.
Magagnoli J, Sutton S, Ambati J
JAMA Ophthalmol
. 2024 Jul;
142(8):759-760.
PMID: 38990521
No abstract available.
5.
Magagnoli J, Sutton S, Ambati J
JAMA Ophthalmol
. 2024 May;
142(7):684-685.
PMID: 38722622
No abstract available.
6.
Gelfand B, Argyle D, Olivieri J, Ambati J
MedComm Futur Med
. 2024 Apr;
2(4).
PMID: 38645476
No abstract available.
7.
Magagnoli J, Cummings T, Hardin J, Sutton S, Ambati J
J Investig Med
. 2024 Apr;
72(6):579-586.
PMID: 38597272
Cisplatin use is often limited by its ototoxic side effects, which can lead to irreversible hearing loss. Preventing cisplatin-induced ototoxicity is crucial to improve patient outcomes. Fluoxetine and fluvoxamine, both...
8.
Kumar A, Nagasaka Y, Jayananthan V, Zidan A, Heisler-Taylor T, Ambati J, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Apr;
1870(5):167156.
PMID: 38582267
Choroidal neovascularization (CNV) is the principal driver of blindness in neovascular age-related macular degeneration (nvAMD). Increased activity of telomerase, has been associated with endothelial cell proliferation, survival, migration, and invasion...
9.
Magliacane Trotta S, Adinolfi A, DOrsi L, Panico S, Mercadante G, Mehlen P, et al.
Exp Mol Med
. 2024 Mar;
56(3):700-710.
PMID: 38486106
Inflammation plays a crucial role in cancer progression, but the relevance of the inflammasome remains unclear. Alu RNA was the first endogenous nucleic acid shown to activate the NLRP3 (nucleotide-binding...
10.
Sutton S, Magagnoli J, Cummings T, Hardin J, Ambati J
JAMA Ophthalmol
. 2024 Jan;
142(2):108-114.
PMID: 38175625
Importance: Age-related macular degeneration (AMD) is a serious and common ophthalmologic disorder that is hypothesized to result, in part, from inflammatory reactions in the macula. Alzheimer disease (AD) treatment, acetylcholinesterase...