Ivana Apicella
Overview
Explore the profile of Ivana Apicella including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
419
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Makin R, Apicella I, Dholkawala R, Fukuda S, Hirahara S, Hirano Y, et al.
Angiogenesis
. 2024 Sep;
27(4):919-929.
PMID: 39316206
Inflammasome activation is implicated in diseases of aberrant angiogenesis such as age-related macular degeneration (AMD), though its precise role in choroidal neovascularization (CNV), a characteristic pathology of advanced AMD, is...
2.
Huang P, Thomas C, Ambati K, Dholkawala R, Nagasaka A, Yerramothu P, et al.
Invest Ophthalmol Vis Sci
. 2023 May;
64(5):3.
PMID: 37129905
Purpose: Rhegmatogenous retinal detachment (RRD) is a vision-threatening event that benefits from surgical intervention. While awaiting surgical reattachment, irreversible hypoxic and inflammatory damage to the retina often occurs. An interim...
3.
Huang P, Narendran S, Pereira F, Fukuda S, Nagasaka Y, Apicella I, et al.
Nat Protoc
. 2022 Apr;
17(6):1468-1485.
PMID: 35418688
Subretinal injection (SRI) is a widely used technique in retinal research and can be used to deliver nucleic acids, small molecules, macromolecules, viruses, cells or biomaterials such as nanobeads. Here...
4.
Huang P, Narendran S, Pereira F, Fukuda S, Nagasaka Y, Apicella I, et al.
Transl Vis Sci Technol
. 2022 Mar;
11(3):13.
PMID: 35275207
Purpose: Subretinal injection (SRI) in mice is widely used in retinal research, yet the learning curve (LC) of this surgically challenging technique is unknown. Methods: To evaluate the LC for...
5.
Wang S, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, et al.
Sci Immunol
. 2021 Dec;
6(66):eabi4493.
PMID: 34860583
Detection of microbial products by multiprotein complexes known as inflammasomes is pivotal to host defense against pathogens. Nucleotide-binding domain leucine-rich repeat (NLR) CARD domain containing 4 (NLRC4) forms an inflammasome...
6.
Ambati M, Apicella I, Wang S, Narendran S, Leung H, Pereira F, et al.
Proc Natl Acad Sci U S A
. 2021 Oct;
118(41).
PMID: 34620711
The atrophic form of age-related macular degeneration (dry AMD) affects nearly 200 million people worldwide. There is no Food and Drug Administration (FDA)-approved therapy for this disease, which is the...
7.
Fukuda S, Narendran S, Varshney A, Nagasaka Y, Wang S, Ambati K, et al.
Sci Adv
. 2021 Sep;
7(40):eabj3658.
PMID: 34586848
Long interspersed nuclear element-1 (L1)–mediated reverse transcription (RT) of RNA into cytoplasmic complementary DNA (cDNA) has been implicated in retinal pigmented epithelium (RPE) degeneration. The mechanism of cDNA–induced cytotoxicity and...
8.
Santonocito M, Zappulla C, Viola S, La Rosa L, Solfato E, Abbate I, et al.
Int J Mol Sci
. 2021 Apr;
22(9).
PMID: 33922399
Eye drop formulations allowing topical treatment of retinal pathologies have long been sought as alternatives to intravitreal administration. This study aimed to assess whether a novel nanostructured microemulsions system (NaMESys)...
9.
Pignata P, Apicella I, Cicatiello V, Puglisi C, Magliacane Trotta S, Sanges R, et al.
Int J Mol Sci
. 2021 Apr;
22(8).
PMID: 33918807
Prolyl 3-hydroxylase 2 () catalyzes the post-translational formation of 3-hydroxyproline on collagens, mainly on type IV. Its activity has never been directly associated to angiogenesis. Here, we identified gene through...
10.
Narendran S, Pereira F, Yerramothu P, Apicella I, Wang S, Ambati K, et al.
Signal Transduct Target Ther
. 2021 Apr;
6(1):149.
PMID: 33850097
Nonfibrillar amyloid-β oligomers (AβOs) are a major component of drusen, the sub-retinal pigmented epithelium (RPE) extracellular deposits characteristic of age-related macular degeneration (AMD), a common cause of global blindness. We...