Jason S Wasserman
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Explore the profile of Jason S Wasserman including associated specialties, affiliations and a list of published articles.
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9
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54
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Recent Articles
1.
Wasserman J, Fowle H, Hashmi R, Atar D, Patel K, Yarmahmoodi A, et al.
Sci Rep
. 2024 Sep;
14(1):20409.
PMID: 39223207
Prostate cancer (PCa) is the most common cancer diagnosed in men worldwide and was the second leading cause of cancer-related deaths in US males in 2022. Prostate cancer also represents...
2.
Wasserman J, Faezov B, Patel K, Kurimchak A, Palacio S, Glass D, et al.
Nat Commun
. 2024 Jul;
15(1):5776.
PMID: 38982062
The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B regulatory subunits. Here, we report the identification of a substrate conserved...
3.
Wasserman J, Fowle H, Hashmi R, Atar D, Patel K, Yarmahmoodi A, et al.
Res Sq
. 2024 May;
PMID: 38766032
Prostate cancer (PCa) is the most common cancer diagnosed in men worldwide and the second leading cause of cancer-related deaths in US males in 2022. Prostate cancer also represents the...
4.
Wasserman J, Feiser F, Palacio S, Patel K, Gonzalez J, Fowle H, et al.
STAR Protoc
. 2023 Apr;
4(2):102148.
PMID: 37074907
Serine/threonine protein phosphatase 2 (PP2A) forms heterotrimeric holoenzymes, where a scaffold subunit bridges the PP2A catalytic subunit to a B regulatory subunit, e.g., B55α. The PP2A/B55α holoenzyme plays key roles...
5.
Wasserman J, Faezov B, Patel K, Kurimchak A, Palacio S, Fowle H, et al.
bioRxiv
. 2023 Mar;
PMID: 36945596
The Ser/Thr protein phosphatase 2A (PP2A) is a highly conserved collection of heterotrimeric holoenzymes responsible for the dephosphorylation of many regulated phosphoproteins. Substrate recognition and the integration of regulatory cues...
6.
Valentine H, Aiken W, Morrison B, Zhao Z, Fowle H, Wasserman J, et al.
Cancer Res Commun
. 2023 Jan;
2(11):1355-1371.
PMID: 36643868
Prostate cell lines from diverse backgrounds are important to addressing disparities in prostate cancer (PCa) incidence and mortality rates among Black men. ACRJ-PC28 was developed from a transrectal needle biopsy...
7.
Fowle H, Zhao Z, Xu Q, Wasserman J, Wang X, Adeyemi M, et al.
Elife
. 2021 Oct;
10.
PMID: 34661528
Protein phosphorylation is a reversible post-translation modification essential in cell signaling. This study addresses a long-standing question as to how the most abundant serine/threonine protein phosphatase 2 (PP2A) holoenzyme, PP2A/B55α,...
8.
Dunlevy K, Medvedeva V, Wilson J, Hoque M, Pellegrin T, Maynard A, et al.
J Cell Sci
. 2020 Apr;
133(10).
PMID: 32317397
A large fraction of epigenetically silent heterochromatin is anchored to the nuclear periphery via 'tethering proteins' that function to bridge heterochromatin and the nuclear membrane or nuclear lamina. We previously...
9.
Zhao Z, Kurimchak A, Nikonova A, Feiser F, Wasserman J, Fowle H, et al.
Oncogenesis
. 2019 Dec;
8(12):72.
PMID: 31822657
The PPP2R2A gene encodes the B55α regulatory subunit of PP2A. Here, we report that PPP2R2A is hemizygously lost in ~42% of prostate adenocarcinomas, correlating with reduced expression, poorer prognosis, and...