Jason S Kuo
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Explore the profile of Jason S Kuo including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
434
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Recent Articles
1.
Zhao M, Schiro P, Kuo J, Koehler K, Sabath D, Popov V, et al.
Anal Chem
. 2013 Feb;
85(4):2465-71.
PMID: 23387387
Enumeration of circulating tumor cells (CTCs) has proved valuable for early detection and prognosis in cancer treatment. This paper describes an automated high-throughput counting method for CTCs based on microfluidics...
2.
Schiro P, Zhao M, Kuo J, Koehler K, Sabath D, Chiu D
Angew Chem Int Ed Engl
. 2012 Feb;
51(19):4618-22.
PMID: 22359315
No abstract available.
3.
Kuo J, Chiu D
Lab Chip
. 2011 Jul;
11(16):2656-65.
PMID: 21727966
As more microfluidic applications emerge for clinical diagnostics, the choice of substrate and production method must be considered for eventual regulatory approval. In this review, we survey recent developments in...
4.
Kuo J, Chiu D
Annu Rev Anal Chem (Palo Alto Calif)
. 2011 Apr;
4:275-96.
PMID: 21456968
Microfluidic platforms offer exquisite capabilities in controlling mass transport for biological studies. In this review, we focus on recent developments in manipulating chemical concentrations at the microscale. Some techniques prevent...
5.
Mutch S, Kensel-Hammes P, Gadd J, Fujimoto B, Allen R, Schiro P, et al.
J Neurosci
. 2011 Jan;
31(4):1461-70.
PMID: 21273430
Protein sorting represents a potential point of regulation in neurotransmission because it dictates the protein composition of synaptic vesicles, the organelle that mediates transmitter release. Although the average number of...
6.
Kuo J, Zhao Y, Schiro P, Ng L, Lim D, Shelby J, et al.
Lab Chip
. 2010 Apr;
10(7):837-42.
PMID: 20379567
Biological cells are highly sensitive to variation in local pressure because cellular membranes are not rigid. Unlike microbeads, cells deform under pressure or even lyse. In isolating or enriching cells...
7.
Kuo J, Zhao Y, Ng L, Yen G, Lorenz R, Lim D, et al.
Lab Chip
. 2009 Jun;
9(13):1951-6.
PMID: 19532971
We recently reported a new UV-curable polyurethane-methacrylate (PUMA) resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production...
8.
Kuo J, Ng L, Yen G, Lorenz R, Schiro P, Edgar J, et al.
Lab Chip
. 2009 Mar;
9(7):870-6.
PMID: 19294296
As microfluidic systems transition from research tools to disposable clinical-diagnostic devices, new substrate materials are needed to meet both the regulatory requirement as well as the economics of disposable devices....
9.
Zhao Y, Schiro P, Kuo J, Ng L, Chiu D
Anal Chem
. 2009 Jan;
81(3):1285-90.
PMID: 19115959
Preparation of calibration standards for cell enumeration is critical in characterizing the performance of any method or apparatus intended for recovering rare cells. Diluting a cell suspension serially is prone...
10.
Handayani S, Chiu D, Tjitra E, Kuo J, Lampah D, Kenangalem E, et al.
J Infect Dis
. 2008 Dec;
199(3):445-50.
PMID: 19090777
Maturation of Plasmodium falciparum decreases the deformability of infected red blood cells (RBCs), increasing their clearance as they attempt to pass through endothelial slits of the splenic sinus. Previous studies...