Yongxi Zhao
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Explore the profile of Yongxi Zhao including associated specialties, affiliations and a list of published articles.
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68
Citations
796
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Recent Articles
1.
Fan S, Li X, Liu H, Ye M, He Y, Fu W, et al.
Angew Chem Int Ed Engl
. 2025 Mar;
:e202425136.
PMID: 40034080
Cellular biomolecules may exhibit dense distribution and organization at the nanoscale to govern vital biological processes. However, it remains a common challenge to digitize the spatially dense biomolecules under spatial...
2.
Chen F, Li X, Bai M, Zhao Y
Nat Protoc
. 2024 Sep;
20(1):220-247.
PMID: 39232201
Epigenetic modifications and spatial proximities of nucleic acids and proteins play important roles in regulating physiological processes and disease progression. Currently available cell imaging methods, such as fluorescence in situ...
3.
Luo Y, Wu N, Niu L, Hao P, Sun X, Chen F, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(15):e2308532.
PMID: 38233163
Single-stranded DNA oligonucleotides wrapping on the surface of single-walled carbon nanotubes (SWCNTs), described as DNA corona, are often used as a dispersing agent for SWCNTs. The uneven distribution of DNA...
4.
Luo Y, Niu L, Hao P, Sun X, Zhao Y, Wu N
Nanoscale
. 2023 Nov;
15(47):19381-19388.
PMID: 38014780
Tannic acid-based patterning is crucial for its applications in bioengineering, including multifunctional coatings, biosensors, and biochips. However, tannic acid (TA) patterning is challenging owing to the rapid polymerization kinetics of...
5.
Li Z, Lv Y, Duan X, Liu B, Zhao Y
Angew Chem Int Ed Engl
. 2023 Sep;
62(45):e202312975.
PMID: 37726209
Assembling DNA on solid surfaces is fundamental to surface-based DNA technology. However, precise control over DNA conformation and organization at solid-liquid interfaces remains a challenge, resulting in limited stability and...
6.
Liu H, Nan L, Chen F, Zhao Y, Zhao Y
Lab Chip
. 2023 May;
23(11):2497-2513.
PMID: 37199118
Droplet microfluidics has emerged as a powerful technology to perform high-throughput experiments, while artificial intelligence (AI) serves as a functional tool to analyze a large set of multiplex data. Their...
7.
Zhang J, Xue J, Luo N, Chen F, Chen B, Zhao Y
Lab Chip
. 2023 Jan;
23(5):1066-1079.
PMID: 36625143
Single-cell profiling is key to uncover the cellular heterogeneity and drives deep understanding of cell fate. In recent years, microfluidics has become an ideal tool for single-cell profiling owing to...
8.
Hierarchical DNA branch assembly-encoded fluorescent nanoladders for single-cell transcripts imaging
Cao X, Chen F, Xue J, Zhao Y, Bai M, Zhao Y
Nucleic Acids Res
. 2022 Dec;
51(3):e13.
PMID: 36478047
Spatial visualization of single-cell transcripts is limited by signal specificity and multiplexing. Here, we report hierarchical DNA branch assembly-encoded fluorescent nanoladders, which achieve denoised and highly multiplexed signal amplification for...
9.
Xue J, Fu Y, Fan S, Cao X, Huang W, Zhang J, et al.
Chem Commun (Camb)
. 2022 Aug;
58(72):10020-10023.
PMID: 35983894
Investigating the spatial information of post-translational modifications (PTMs) in distinct cell subpopulations represents a new direction toward single-cell analysis. The specific capture of cell populations combined with PTM spatial proximity...
10.
Chen F, Xue J, Bai M, Fan C, Zhao Y
Acc Chem Res
. 2022 Jul;
55(16):2248-2259.
PMID: 35904502
Nucleic acids are naturally decorated with various chemical modifications at nucleobases. Most nucleic acid modifications (NAMs) do not alter Watson-Crick base pairing but can regulate gene expression known as "epigenetics"....