Robert M Lorenz
Overview
Explore the profile of Robert M Lorenz including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
427
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Recent Articles
1.
Mutch S, Kensel-Hammes P, Gadd J, Fujimoto B, Allen R, Schiro P, et al.
J Neurosci
. 2011 Jan;
31(4):1461-70.
PMID: 21273430
Protein sorting represents a potential point of regulation in neurotransmission because it dictates the protein composition of synaptic vesicles, the organelle that mediates transmitter release. Although the average number of...
2.
Jeffries G, Lorenz R, Chiu D
Anal Chem
. 2010 Nov;
82(23):9948-54.
PMID: 21062029
This paper describes a simple modification to traditional confocal fluorescence detection that greatly improves signal-to-noise (s/n) for the high-speed analysis of droplet streams. Rather than using the conventional epi geometry,...
3.
Kuo J, Zhao Y, Ng L, Yen G, Lorenz R, Lim D, et al.
Lab Chip
. 2009 Jun;
9(13):1951-6.
PMID: 19532971
We recently reported a new UV-curable polyurethane-methacrylate (PUMA) resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production...
4.
Chiu D, Lorenz R, Jeffries G
Anal Chem
. 2009 Jun;
81(13):5111-8.
PMID: 19507850
By using methods that permit the generation and manipulation of ultrasmall-volume droplets, researchers are pushing the boundaries of ultrasensitive chemical analyses. (To listen to a podcast about this feature, please...
5.
Kuo J, Ng L, Yen G, Lorenz R, Schiro P, Edgar J, et al.
Lab Chip
. 2009 Mar;
9(7):870-6.
PMID: 19294296
As microfluidic systems transition from research tools to disposable clinical-diagnostic devices, new substrate materials are needed to meet both the regulatory requirement as well as the economics of disposable devices....
6.
Chiu D, Lorenz R
Acc Chem Res
. 2009 Mar;
42(5):649-58.
PMID: 19260732
The basic unit of any biological system is the cell, and malfunctions at the single-cell level can result in devastating diseases; in cancer metastasis, for example, a single cell seeds...
7.
Lorenz R, Fiorini G, Jeffries G, Lim D, He M, Chiu D
Anal Chim Acta
. 2008 Nov;
630(2):124-30.
PMID: 19012823
This paper describes a microfluidic platform for the on-demand generation of multiple aqueous droplets, with varying chemical contents or chemical concentrations, for use in droplet based experiments. This generation technique...
8.
Fiorini G, Yim M, Jeffries G, Schiro P, Mutch S, Lorenz R, et al.
Lab Chip
. 2007 Jun;
7(7):923-6.
PMID: 17594014
Thermoset polyester (TPE) microfluidic devices were previously developed as an alternative to poly(dimethylsiloxane) (PDMS) devices, fabricated similarly by replica molding, yet offering stable surface properties and good chemical compatibility with...
9.
Lorenz R, Edgar J, Jeffries G, Zhao Y, McGloin D, Chiu D
Anal Chem
. 2006 Dec;
79(1):224-8.
PMID: 17194143
This paper describes the use of an optical vortex trap for the transport and fusion of single femtoliter-volume aqueous droplets. Individual droplets were generated by emulsifying water in acetophenone with...
10.
Edgar J, Pabbati C, Lorenz R, He M, Fiorini G, Chiu D
Anal Chem
. 2006 Sep;
78(19):6948-54.
PMID: 17007519
This paper demonstrates the ability to use capillary electrophoresis (CE) separation coupled with laser-induced fluorescence for analyzing the contents of single femtoliter-volume aqueous droplets. A single droplet was formed using...