Jason S Chapman
Overview
Explore the profile of Jason S Chapman including associated specialties, affiliations and a list of published articles.
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3
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23
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Recent Articles
1.
Anding A, Chapman J, Barnett D, Curley Jr R, Clagett-Dame M
Cancer Res
. 2007 Jul;
67(13):6270-7.
PMID: 17616685
The synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) induces apoptosis in a variety of cell lines and has shown promise as an anticancer agent both in vitro and in vivo. The clinical dose...
2.
Mershon S, Anding A, Chapman J, Clagett-Dame M, Stonerock L, Curley Jr R
Bioorg Med Chem Lett
. 2006 Nov;
17(3):836-40.
PMID: 17112722
Using solid phase-assisted synthesis and purification, a 49 member library of analogs of the mammary tumor chemopreventive retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) has been prepared. After prescreening for growth inhibitory activity in...
3.
Chapman J, Weiss K, Curley Jr R, Highland M, Clagett-Dame M
Arch Biochem Biophys
. 2003 Nov;
419(2):234-43.
PMID: 14592467
The retinamide, N-(4-hydroxyphenyl)retinamide (4-HPR), has shown promising anti-tumor activity, but it is unclear whether this compound is hydrolyzed to all-trans retinoic acid (atRA) and if so, whether this plays any...