Jason R Richardson
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Explore the profile of Jason R Richardson including associated specialties, affiliations and a list of published articles.
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126
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3443
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Recent Articles
1.
Mhatre-Winters I, Eid A, Blum N, Han Y, Sammoura F, Wu L, et al.
bioRxiv
. 2025 Mar;
PMID: 40027678
Background: Alzheimer's disease (AD) is characterized by the presence of amyloid-β plaques, neurofibrillary tangles, and neuroinflammation. Previously, we reported serum levels of dichlorodiphenyldichloroethylene (DDE), the primary metabolite of the pesticide...
2.
Kasanga E, Soto I, Centner A, McManus R, Shifflet M, Navarrete W, et al.
Exp Neurol
. 2024 Jun;
379:114875.
PMID: 38944332
Alleviation of motor impairment by aerobic exercise (AE) in Parkinson's disease (PD) patients points to activation of neurobiological mechanisms that may be targetable by therapeutic approaches. However, evidence for AE-related...
3.
Wang L, Zheng J, Zhao S, Wan Y, Wang M, Bosco D, et al.
Cell Rep
. 2024 Apr;
43(4):114120.
PMID: 38625796
Border-associated macrophages (BAMs) are tissue-resident macrophages that reside at the border of the central nervous system (CNS). Since BAMs originate from yolk sac progenitors that do not persist after birth,...
4.
Fan R, Sportelli C, Lai Y, Salehe S, Pinnell J, Brown H, et al.
Mol Neurodegener
. 2024 Mar;
19(1):26.
PMID: 38504290
Background: Dynamin-related protein 1 (Drp1) plays a critical role in mitochondrial dynamics. Partial inhibition of this protein is protective in experimental models of neurological disorders such as Parkinson's disease and...
5.
Godieva V, Sammoura F, Verrier Paz S, Han Y, Di Guida V, Rishel M, et al.
bioRxiv
. 2024 Jan;
PMID: 38293240
The c-Jun N-terminal kinase 3 (JNK3) is a stress-responsive protein kinase primarily expressed in the central nervous system (CNS). JNK3 exhibits nuanced neurological activities, such as roles in behavior, circadian...
6.
Kasanga E, Han Y, Shifflet M, Navarrete W, McManus R, Parry C, et al.
Exp Neurol
. 2023 Aug;
368:114509.
PMID: 37634696
Compensatory mechanisms that augment dopamine (DA) signaling are thought to mitigate onset of hypokinesia prior to major loss of tyrosine hydroxylase (TH) in striatum that occurs in Parkinson's disease. However,...
7.
Marinello W, Gillera S, Han Y, Richardson J, St Armour G, Horman B, et al.
Mol Cell Endocrinol
. 2023 Aug;
576:112041.
PMID: 37562579
Gestational flame retardant (FR) exposure has been linked to heightened risk of neurodevelopmental disorders, but the mechanisms remain largely unknown. Historically, toxicologists have relied on traditional, inbred rodent models, yet...
8.
Kasanga E, Soto I, Centner A, McManus R, Shifflet M, Navarrete W, et al.
bioRxiv
. 2023 Jul;
PMID: 37502851
Background: Alleviation of motor impairment by aerobic exercise (AE) in Parkinson's disease (PD) points to a CNS response that could be targeted by therapeutic approaches, but recovery of striatal dopamine...
9.
Fan R, Sportelli C, Lai Y, Salehe S, Pinnell J, Richardson J, et al.
bioRxiv
. 2023 Jul;
PMID: 37425803
Dynamin-related protein 1 (Drp1) is typically known for its role in mitochondrial fission. A partial inhibition of this protein has been reported to be protective in experimental models of neurodegenerative...
10.
Zhao S, Zheng J, Wang L, Umpierre A, Parusel S, Xie M, et al.
Mol Psychiatry
. 2023 Jun;
28(7):2857-2871.
PMID: 37365239
Chemogenetic approaches using Designer Receptors Exclusively Activated by Designer Drugs (DREADD, a family of engineered GPCRs) were recently employed in microglia. Here, we used Cx3cr1:R26 mice to express Gi-DREADD (hM4Di)...