Jason R Richardson
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Explore the profile of Jason R Richardson including associated specialties, affiliations and a list of published articles.
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126
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3443
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Recent Articles
11.
Kasanga E, Han Y, Navarrete W, McManus R, Shifflet M, Parry C, et al.
Exp Neurol
. 2023 May;
366:114435.
PMID: 37178997
Although glial cell line-derived neurotrophic factor (GDNF) showed efficacy in preclinical and early clinical studies to alleviate parkinsonian signs in Parkinson's disease (PD), later trials did not meet primary endpoints,...
12.
Neal M, Beier E, Hossain M, Boyle A, Zheng J, Kim C, et al.
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978830
Although the precise mechanisms for neurodegeneration in Parkinson's disease (PD) are unknown, evidence suggests that neuroinflammation is a critical factor in the pathogenic process. Here, we sought to determine whether...
13.
Kasanga E, Han Y, Navarrete W, McManus R, Shifflet M, Parry C, et al.
bioRxiv
. 2023 Mar;
PMID: 36909534
Significance Statement: Although preclinical evidence supports that GDNF provides neuroprotection and improves locomotor function in preclinical studies, clinical data supporting its efficacy to alleviate motor impairment in Parkinson's disease patients...
14.
Mhatre-Winters I, Eid A, Han Y, Tieu K, Richardson J
ASN Neuro
. 2023 Jan;
15:17590914221144549.
PMID: 36604975
Apolipoprotein E4 (APOE4) genotype and sex are significant risk factors for Alzheimer's disease (AD), with females demonstrating increased risk modulated by APOE genotype. APOE is predominantly expressed in astrocytes, however,...
15.
Sammoura F, Popova D, Morris A, Hart R, Richardson J
Curr Res Neurobiol
. 2023 Jan;
4:100069.
PMID: 36589676
Primary neuronal cultures have proven to be a powerful tool for studying mechanisms in neuroscience. It is technically challenging and expensive to reproduce high quality viable neuronal cultures. Laboratories that...
16.
Mishin V, Heck D, Jan Y, Richardson J, Laskin J
Toxicol Appl Pharmacol
. 2022 Sep;
455:116258.
PMID: 36174671
A characteristic of cytochrome P450 (CYP) enzymes is their ability to generate HO, either directly or indirectly via superoxide anion, a reaction referred to as "NADPH oxidase" activity. HO production...
17.
Mhatre-Winters I, Eid A, Han Y, Tieu K, Richardson J
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077227
The sex and APOE4 genotype are significant risk factors for Alzheimer’s disease (AD); however, the mechanism(s) responsible for this interaction are still a matter of debate. Here, we assess the...
18.
Eid A, Mhatre-Winters I, Sammoura F, Edler M, von Stein R, Hossain M, et al.
Environ Health Perspect
. 2022 Aug;
130(8):87005.
PMID: 35946953
Background: The interaction of aging-related, genetic, and environmental factors is thought to contribute to the etiology of late-onset, sporadic Alzheimer's disease (AD). We previously reported that serum levels of '-dichlorodiphenyldichloroethylene...
19.
Moser V, Morris-Schaffer K, Richardson J, Li A
J Toxicol Environ Health B Crit Rev
. 2022 Jun;
25(4):162-209.
PMID: 35676826
Studies of nervous system effects of glyphosate, a widely used herbicide, have not been critically examined. The aim of this paper was to systematically review glyphosate-induced neurotoxicity literature to determine...
20.
Barahona A, Bursac Z, Veledar E, Lucchini R, Tieu K, Richardson J
Toxics
. 2022 Apr;
10(4).
PMID: 35448452
Manganese (Mn) is an essential metal with a biphasic relationship with health outcomes. High-level exposure to Mn is associated with manganism, but few data explore the effects of chronic, lower-level...