Jason R Pirone
Overview
Explore the profile of Jason R Pirone including associated specialties, affiliations and a list of published articles.
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14
Citations
430
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0
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Recent Articles
1.
Fuller A, Yang L, Hamilton A, Pirone J, Oldenburg A, Troester M
J Mammary Gland Biol Neoplasia
. 2021 Jan;
26(2):89-99.
PMID: 33439408
Basal-like breast cancers (BBC) exhibit subtype-specific phenotypic and transcriptional responses to stroma, but little research has addressed how stromal-epithelial interactions evolve during early BBC carcinogenesis. It is also unclear how...
2.
Devanathan A, Fallon J, White N, Schauer A, Van Horne B, Blake K, et al.
Antimicrob Agents Chemother
. 2020 Jul;
64(10).
PMID: 32661005
Adequate antiretroviral (ARV) concentrations in lymphoid tissues are critical for optimal antiretroviral therapy (ART). While the spleen contains 25% of the body's lymphocytes, there are minimal data on ARV penetration...
3.
Devanathan A, Pirone J, Akkina R, Remling-Mulder L, Luciw P, Adamson L, et al.
Antimicrob Agents Chemother
. 2019 Oct;
64(1).
PMID: 31611355
For HIV cure strategies like "kick and kill" to succeed, antiretroviral (ARV) drugs must reach effective concentrations in putative viral reservoirs. We characterize penetration of six ARVs in three preclinical...
4.
Krovi S, Gallovic M, Keller A, Bhat M, Tiet P, Chen N, et al.
Int J Pharm
. 2018 Oct;
552(1-2):371-377.
PMID: 30308272
While highly active antiretroviral therapy (HAART) has significantly reduced mortality rates in patients with human immunodeficiency virus type 1 (HIV-1), its efficacy may be impeded by emergence of drug resistance...
5.
Alexander G, Farris S, Pirone J, Zheng C, Colgin L, Dudek S
Nat Commun
. 2016 Jan;
7:10300.
PMID: 26806606
The hippocampus supports a cognitive map of space and is critical for encoding declarative memory (who, what, when and where). Recent studies have implicated hippocampal subfield CA2 in social and...
6.
Aupperlee M, Zhao Y, Tan Y, Zhu Y, Langohr I, Kirk E, et al.
Breast Cancer Res
. 2015 Nov;
17(1):138.
PMID: 26526858
Introduction: Increased animal fat consumption is associated with increased premenopausal breast cancer risk in normal weight, but not overweight, women. This agrees with our previous findings in obesity-resistant BALB/c mice,...
7.
Boyd W, Smith M, Co C, Pirone J, Rice J, Shockley K, et al.
Environ Health Perspect
. 2015 Oct;
124(5):586-93.
PMID: 26496690
Background: Modern toxicology is shifting from an observational to a mechanistic science. As part of this shift, high-throughput toxicity assays are being developed using alternative, nonmammalian species to prioritize chemicals...
8.
Pirone J, Smith M, Kleinstreuer N, Burns T, Strickland J, Dancik Y, et al.
ALTEX
. 2014 Apr;
31(3):336-40.
PMID: 24687303
An open-source implementation of a previously published integrated testing strategy (ITS) for skin sensitization using a Bayesian network has been developed using R, a free and open-source statistical computing language....
9.
Pirone J, DArcy M, Stewart D, Hines W, Johnson M, Gould M, et al.
Cancer Epidemiol Biomarkers Prev
. 2012 Aug;
21(10):1735-44.
PMID: 22859400
Background: Age is the strongest breast cancer risk factor, with overall breast cancer risk increasing steadily beginning at approximately 30 years of age. However, while breast cancer risk is lower...
10.
Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients
Roman-Perez E, Casbas-Hernandez P, Pirone J, Rein J, Carey L, Lubet R, et al.
Breast Cancer Res
. 2012 Mar;
14(2):R51.
PMID: 22429463
Introduction: A gene expression signature indicative of activated wound responses is common to more than 90% of non-neoplastic tissues adjacent to breast cancer, but these tissues also exhibit substantial heterogeneity....