Angela D M Kashuba
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Explore the profile of Angela D M Kashuba including associated specialties, affiliations and a list of published articles.
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193
Citations
3846
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Recent Articles
1.
Devanathan A, Poliseno A, White N, Schauer A, Sykes C, Weideman A, et al.
J Acquir Immune Defic Syndr
. 2025 Jan;
98(3):291-299.
PMID: 39813294
Background: Incomplete adherence to daily tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) reduces effectiveness. Adherence biomeasures (ie, drug concentrations in biological specimen) are more accurate than self-report. TDF/FTC's intracellular active metabolites (tenofovir-diphosphate; TFVdp...
2.
Dahl D, Srinivasan P, Janusziewicz R, King J, Shrivastava R, Zhang J, et al.
J Control Release
. 2024 Nov;
376:1209-1224.
PMID: 39500407
Globally, nearly half of all pregnancies are unintended, ∼1.3 million new human immunodeficiency virus (HIV) infections are reported every year, and more than 500 million people are estimated to have...
3.
Kinsale T, Cottrell M, Li L, Brand R, Gatto G, Luecke E, et al.
Pharmaceutics
. 2024 Feb;
16(2).
PMID: 38399255
Long-acting injectable cabotegravir is more effective than daily oral PrEP at preventing HIV transmission due to improved adherence, but requires bi-monthly large-volume intramuscular injections. Subcutaneous (SC) contraceptive implants can be...
4.
Young I, Massud I, Cottrell M, Shrivastava R, Maturavongsadit P, Prasher A, et al.
Nat Commun
. 2024 Feb;
15(1):1054.
PMID: 38316836
No abstract available.
5.
Elizaldi S, Verma A, Ma Z, Ott S, Rajasundaram D, Hawes C, et al.
PLoS Pathog
. 2023 Dec;
19(12):e1011844.
PMID: 38060615
Virologic suppression with antiretroviral therapy (ART) has significantly improved health outcomes for people living with HIV, yet challenges related to chronic inflammation in the central nervous system (CNS)-known as Neuro-HIV-...
6.
Leung E, Cottrell M, Sykes C, White N, Kashuba A, Dumond J
CPT Pharmacometrics Syst Pharmacol
. 2023 Oct;
12(12):1922-1930.
PMID: 37814498
A priori use of mathematical modeling and simulation to predict outcomes from incomplete adherence or reduced frequency dosing strategies may mitigate the risk of clinical trial failure with HIV pre-exposure...
7.
Young I, Pallerla A, Cottrell M, Maturavongsadit P, Prasher A, Shrivastava R, et al.
J Control Release
. 2023 Oct;
363:606-620.
PMID: 37797892
Only condoms are proven to protect against both HIV and unplanned pregnancy, however, poor user acceptability and lack of partner cooperation impede effectiveness. We developed an injectable ultra-long-acting, biodegradable, and...
8.
Elizaldi S, Verma A, Ma Z, Ott S, Rajasundaram D, Cottrell M, et al.
bioRxiv
. 2023 Sep;
PMID: 37662237
Virologic suppression with antiretroviral therapy (ART) has significantly improved health outcomes for people living with HIV, yet challenges related to chronic inflammation in the central nervous system (CNS) - known...
9.
Young I, Srinivasan P, Shrivastava R, Janusziewicz R, Thorson A, Cottrell M, et al.
Biomaterials
. 2023 Aug;
301:122260.
PMID: 37549505
Globally, there are 20 million adolescent girls and young women living with HIV who have limited access to long-acting, effective, women-controlled preventative methods. Additionally, although there are many contraceptive methods...
10.
Desyaterik Y, Mwangi J, McRae M, Jones A, Kashuba A, Rosen E
Anal Bioanal Chem
. 2023 Jul;
415(23):5809-5817.
PMID: 37490153
Here, we present a method developed for the analysis of spatial distributions of morphine in mouse brain tissue using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) coupled to a Q...