Jason P Gardner
Overview
Explore the profile of Jason P Gardner including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
571
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Recent Articles
1.
McNeish J, Gardner J, Wainger B, Woolf C, Eggan K
Cell Stem Cell
. 2015 Jul;
17(1):8-10.
PMID: 26140603
While iPSCs have created unprecedented opportunities for drug discovery, there remains uncertainty concerning the path to the clinic for candidate therapeutics discovered with their use. Here we share lessons that...
2.
Ravaud A, Hawkins R, Gardner J, von der Maase H, Zantl N, Harper P, et al.
J Clin Oncol
. 2008 May;
26(14):2285-91.
PMID: 18467719
Purpose: Lapatinib is an orally reversible inhibitor of epidermal growth factor receptor (EGFR)/human epidermal growth factor receptor 2 (HER-2) tyrosine kinases with demonstrated activity in patients with HER-2-positive breast cancer....
3.
Durso R, Andjelic S, Gardner J, Margitich D, Donovan G, Arrigale R, et al.
Clin Cancer Res
. 2007 Jul;
13(13):3999-4008.
PMID: 17606734
Purpose: Prostate-specific membrane antigen (PSMA) is an attractive target for active immunotherapy. Alphavirus vaccines have shown promise in eliciting immunity to tumor antigens. This study investigated the immunogenicity of alphavirus...
4.
Falkowska E, Durso R, Gardner J, Cormier E, Arrigale R, Ogawa R, et al.
J Gen Virol
. 2006 Aug;
87(Pt 9):2571-2576.
PMID: 16894195
L-SIGN is a C-type lectin that is expressed on liver sinusoidal endothelial cells. Capture of Hepatitis C virus (HCV) by this receptor results in trans-infection of hepatoma cells. L-SIGN alleles...
5.
Goldberg S, Bartido S, Gardner J, Guevara-Patino J, Montgomery S, Perales M, et al.
Clin Cancer Res
. 2005 Nov;
11(22):8114-21.
PMID: 16299244
Purpose: Immunization of mice with xenogeneic DNA encoding human tyrosinase-related proteins 1 and 2 breaks tolerance to these self-antigens and leads to tumor rejection. Viral vectors used alone or in...
6.
Cormier E, Durso R, Tsamis F, Boussemart L, Manix C, Olson W, et al.
Proc Natl Acad Sci U S A
. 2004 Sep;
101(39):14067-72.
PMID: 15371595
Target cell tropism of enveloped viruses is regulated by interactions between viral and cellular factors during transmission, dissemination, and replication within the host. Binding of viral envelope glycoproteins to specific...
7.
Cormier E, Tsamis F, Kajumo F, Durso R, Gardner J, Dragic T
Proc Natl Acad Sci U S A
. 2004 May;
101(19):7270-4.
PMID: 15123813
Hepatitis C virus (HCV) envelope glycoproteins E1/E2 can pseudotype retroviral particles and efficiently mediate entry into target cells. Using this experimental system, we determined HCV tropism for different cell types....
8.
Dumonceaux J, Cormier E, Kajumo F, Donovan G, Roy-Chowdhury J, Fox I, et al.
J Virol
. 2003 Dec;
77(24):13418-24.
PMID: 14645599
Hepatitis C virus (HCV) is a positive-strand RNA virus that replicates exclusively in the cytoplasm of infected cells. The viral envelope glycoproteins, E1 and E2, appear to be retained in...
9.
Schulke N, Varlamova O, Donovan G, Ma D, Gardner J, Morrissey D, et al.
Proc Natl Acad Sci U S A
. 2003 Oct;
100(22):12590-5.
PMID: 14583590
Prostate-specific membrane antigen (PSMA) is a type 2 integral membrane glycoprotein that serves as an attractive target for cancer immunotherapy by virtue of its abundant and restricted expression on the...
10.
Gardner J, Durso R, Arrigale R, Donovan G, Maddon P, Dragic T, et al.
Proc Natl Acad Sci U S A
. 2003 Apr;
100(8):4498-503.
PMID: 12676990
Hepatitis C virus (HCV) infects nearly 3% of the population of the world and is a major cause of liver disease. However, the mechanism whereby the virus targets the liver...