Jason M Schenkel
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Explore the profile of Jason M Schenkel including associated specialties, affiliations and a list of published articles.
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52
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7066
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Recent Articles
1.
Hagan N, Inaku C, Kunder N, White T, Iraguha T, Meyer A, et al.
J Immunol
. 2025 Mar;
PMID: 40073090
Leukocytes migrate through the blood and extravasate into organs to surveil the host for infection or cancer. Recently, we demonstrated that intravenous (IV) anti-CD45.2 antibody labeling allowed for precise tracking...
2.
Mahuron K, Shahid O, Sao P, Wu C, Haugh A, Huppert L, et al.
Cancer Res
. 2025 Mar;
PMID: 40042995
PD-1 pathway inhibitors have revolutionized cancer therapy. However, most patients do not durably benefit, highlighting the need for biomarkers to stratify patients as responders or non-responders. While CD8+ tumor infiltrating...
3.
Gonta R, Schenkel J, Klein K, Martinez F, Medina M
Transfus Med
. 2024 Nov;
PMID: 39601217
Background: Granulocyte transfusions represent a therapeutic option for severely neutropenic patients with bacterial or fungal infections that are otherwise unresponsive to conventional therapy. Prior clinical studies suggest that patients receiving...
4.
Hagan N, Inaku C, Kunder N, White T, Iraguha T, Meyer A, et al.
bioRxiv
. 2024 Aug;
PMID: 39149319
Leukocytes migrate through the blood and extravasate into organs to surveil the host for infection or cancer. Recently, we demonstrated that intravenous (IV) anti-CD45.2 antibody labeling allowed for precise tracking...
5.
Shanahan S, Kunder N, Inaku C, Hagan N, Gibbons G, Mathey-Andrews N, et al.
J Immunol
. 2024 Jul;
213(6):906-918.
PMID: 39082930
Anticancer immunity is predicated on leukocyte migration into tumors. Once recruited, leukocytes undergo substantial reprogramming to adapt to the tumor microenvironment. A major challenge in the field is distinguishing recently...
6.
Schenkel J, Pauken K
Nat Rev Immunol
. 2023 May;
23(12):807-823.
PMID: 37253877
Tissue localization is a critical determinant of T cell immunity. CD8 T cells are contact-dependent killers, which requires them to physically be within the tissue of interest to kill peptide-MHC...
7.
Rosato P, Lotfi-Emran S, Joag V, Wijeyesinghe S, Quarnstrom C, Degefu H, et al.
Mucosal Immunol
. 2023 Jan;
16(1):17-26.
PMID: 36657662
Adaptive immunity is didactically partitioned into humoral and cell-mediated effector mechanisms, which may imply that each arm is separate and does not function together. Here, we report that the activation...
8.
Naranjo S, Cabana C, LaFave L, Romero R, Shanahan S, Bhutkar A, et al.
Genes Dev
. 2022 Sep;
36(15-16):936-949.
PMID: 36175034
Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (LUAD), the most common histological subtype, accounts for 40% of all cases. While existing genetically engineered mouse models...
9.
Hwang W, Jagadeesh K, Guo J, Hoffman H, Yadollahpour P, Reeves J, et al.
Nat Genet
. 2022 Jul;
54(8):1178-1191.
PMID: 35902743
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we...
10.
Jaeger A, Stopfer L, Ahn R, Sanders E, Sandel D, Freed-Pastor W, et al.
Nature
. 2022 Jun;
607(7917):149-155.
PMID: 35705813
Immunosurveillance of cancer requires the presentation of peptide antigens on major histocompatibility complex class I (MHC-I) molecules. Current approaches to profiling of MHC-I-associated peptides, collectively known as the immunopeptidome, are...