Jason L Nathanson
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Explore the profile of Jason L Nathanson including associated specialties, affiliations and a list of published articles.
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8
Citations
529
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Recent Articles
1.
Luo E, Nathanson J, Tan F, Schwartz J, Schmok J, Shankar A, et al.
Nat Struct Mol Biol
. 2020 Aug;
27(10):989-1000.
PMID: 32807991
The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting a major bottleneck to a full understanding of gene expression regulation. Here, we develop a plasmid resource...
2.
DAntonio M, Woodruff G, Nathanson J, DAntonio-Chronowska A, Arias A, Matsui H, et al.
Stem Cell Reports
. 2017 Apr;
8(4):1101-1111.
PMID: 28410643
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in cell types difficult to extract from living patients, such...
3.
Lippi G, Fernandes C, Ewell L, John D, Romoli B, Curia G, et al.
Neuron
. 2016 Dec;
92(6):1337-1351.
PMID: 27939580
A critical feature of neural networks is that they balance excitation and inhibition to prevent pathological dysfunction. How this is achieved is largely unknown, although deficits in the balance contribute...
4.
Marchetto M, Narvaiza I, Denli A, Benner C, Lazzarini T, Nathanson J, et al.
Nature
. 2013 Oct;
503(7477):525-529.
PMID: 24153179
Identifying cellular and molecular differences between human and non-human primates (NHPs) is essential to the basic understanding of the evolution and diversity of our own species. Until now, preserved tissues...
5.
Wilbert M, Huelga S, Kapeli K, Stark T, Liang T, Chen S, et al.
Mol Cell
. 2012 Sep;
48(2):195-206.
PMID: 22959275
LIN28 is a conserved RNA-binding protein implicated in pluripotency, reprogramming, and oncogenesis. It was previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, but here we elucidate distinct...
6.
Andrade L, Nathanson J, Yeo G, Menck C, Muotri A
Hum Mol Genet
. 2012 Jun;
21(17):3825-34.
PMID: 22661500
Cockayne syndrome (CS) is a human premature aging disorder associated with neurological and developmental abnormalities, caused by mutations mainly in the CS group B gene (ERCC6). At the molecular level,...
7.
Heider B, Nathanson J, Isacoff E, Callaway E, Siegel R
PLoS One
. 2010 Nov;
5(11):e13829.
PMID: 21079806
Two-photon scanning microscopy has advanced our understanding of neural signaling in non-mammalian species and mammals. Various developments are needed to perform two-photon scanning microscopy over prolonged periods in non-human primates...
8.
Nathanson J, Jappelli R, Scheeff E, Manning G, Obata K, Brenner S, et al.
Front Neural Circuits
. 2009 Dec;
3:19.
PMID: 19949461
Short cell-type specific promoter sequences are important for targeted gene therapy and studies of brain circuitry. We report on the ability of short promoter sequences to drive fluorescent protein expression...