Jason Greenbaum
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Explore the profile of Jason Greenbaum including associated specialties, affiliations and a list of published articles.
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2988
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Recent Articles
1.
Vita R, Blazeska N, Marrama D, Duesing S, Bennett J, Greenbaum J, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D436-D443.
PMID: 39558162
Over the past 20 years, the Immune Epitope Database (IEDB, iedb.org) has established itself as the foremost resource for immune epitope data. The IEDB catalogs published epitopes and their contextual...
2.
Miller A, Kosaloglu-Yalcin Z, Westernberg L, Montero L, Bahmanof M, Frentzen A, et al.
Sci Transl Med
. 2024 Feb;
16(736):eabj9905.
PMID: 38416845
The clinical impact of tumor-specific neoantigens as both immunotherapeutic targets and biomarkers has been impeded by the lack of efficient methods for their identification and validation from routine samples. We...
3.
Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramirez-Suastegui C, Castelan V, et al.
Sci Immunol
. 2023 Nov;
8(89):eabn8531.
PMID: 37948512
Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes that respond to microbial metabolites. We defined MAIT cell populations in different organs and characterized the developmental pathway of...
4.
Mendes M, Mahita J, Blazeska N, Greenbaum J, Ha B, Wheeler K, et al.
Protein Sci
. 2023 Feb;
32(4):e4605.
PMID: 36806329
The Immune Epitope Database (IEDB) catalogs T cell, B cell, and major histocompatibility complex ligand information in the context of infectious disease, allergy, autoimmunity, and transplantation. An important component of...
5.
Gutman I, Gutman R, Sidney J, Chihab L, Mishto M, Liepe J, et al.
ACS Omega
. 2022 Jul;
7(27):23771-23781.
PMID: 35847273
Synthetic peptides are commonly used in biomedical science for many applications in basic and translational research. While peptide synthesis is generally easy and reliable, the chemical nature of some amino...
6.
Grifoni A, Voic H, Yu E, Mateus J, Yan Fung K, Wang A, et al.
Vaccines (Basel)
. 2022 Apr;
10(4).
PMID: 35455361
While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of...
7.
McCann K, von Witzleben A, Thomas J, Wang C, Wood O, Singh D, et al.
J Immunother Cancer
. 2022 Apr;
10(3).
PMID: 35361728
Background: Cancer is characterized by an accumulation of somatic mutations, of which a significant subset can generate cancer-specific neoepitopes that are recognized by autologous T cells. Such neoepitopes are emerging...
8.
Kosaloglu-Yalcin Z, Lee J, Greenbaum J, Schoenberger S, Miller A, Kim Y, et al.
iScience
. 2022 Feb;
25(2):103850.
PMID: 35128348
Many steps of the MHC class I antigen processing pathway can be predicted using computational methods. Here we show that epitope predictions can be further improved by considering abundance levels...
9.
Murray M, Engel I, Seumois G, Herrera-De La Mata S, Rosales S, Sethi A, et al.
Nat Commun
. 2021 Mar;
12(1):1446.
PMID: 33664261
Invariant natural killer T cells (iNKT cells) differentiate into thymic and peripheral NKT1, NKT2 and NKT17 subsets. Here we use RNA-seq and ATAC-seq analyses and show iNKT subsets are similar,...
10.
Rydyznski Moderbacher C, Ramirez S, Dan J, Grifoni A, Hastie K, Weiskopf D, et al.
Cell
. 2020 Oct;
183(4):996-1012.e19.
PMID: 33010815
Limited knowledge is available on the relationship between antigen-specific immune responses and COVID-19 disease severity. We completed a combined examination of all three branches of adaptive immunity at the level...