Jason Defuria
Overview
Explore the profile of Jason Defuria including associated specialties, affiliations and a list of published articles.
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15
Citations
1246
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Recent Articles
1.
Mertes P, Collange O, Coliat P, Banerjee M, Diringer M, Roche A, et al.
J Control Release
. 2021 Jun;
336:252-261.
PMID: 34175365
Current therapeutic treatments improving the impaired transportation of oxygen in acute respiratory distress syndrome (ARDS) have been found to be relevant and beneficial for the therapeutic treatment of COVID-19 patients...
2.
Huang M, Liu Z, Baugh L, Defuria J, Maione A, Smith A, et al.
Lab Invest
. 2018 Dec;
99(4):514-527.
PMID: 30568176
Cutaneous fibrosis is a common complication seen in mixed connective tissue diseases. It often occurs as a result of TGF-β-induced deposition of excessive amounts of collagen in the skin. Lysyl...
3.
Lewis E, Ren Z, Defuria J, Obin M, Meydani S, Wu D
Br J Nutr
. 2018 May;
119(12):1393-1399.
PMID: 29845904
Blueberry, rich in antioxidant and anti-inflammatory phytochemicals, has been demonstrated to lower inflammatory status in adipose induced by high-fat diet (HFD) and obesity. The effect of blueberry on systemic immune...
4.
Ip B, Cilfone N, Belkina A, Defuria J, Jagannathan-Bogdan M, Zhu M, et al.
Obesity (Silver Spring)
. 2015 Nov;
24(1):102-12.
PMID: 26576827
Objective: T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM). The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding...
5.
Zhu M, Belkina A, Defuria J, Carr J, Van Dyke T, Gyurko R, et al.
J Leukoc Biol
. 2014 May;
96(2):349-57.
PMID: 24782490
Individuals with T2D and PD suffer significantly from the ability of one disease to intensify the other. Disease-associated inflammation is one mechanism thought to fuel this pathogenic feed-forward loop. Several...
6.
Canaan A, Defuria J, Perelman E, Schultz V, Seay M, Tuck D, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(14):5313-8.
PMID: 24706839
The HLA-F adjacent transcript 10 (FAT10) is a member of the ubiquitin-like gene family that alters protein function/stability through covalent ligation. Although FAT10 is induced by inflammatory mediators and implicated...
7.
Bennett G, Strissel K, Defuria J, Wang J, Wu D, Burkly L, et al.
Obesity (Silver Spring)
. 2014 Mar;
22(6):1485-94.
PMID: 24616441
Objective: To investigate the role of TNF-like weak inducer of apoptosis (TWEAK) in pathological adipose tissue (AT) remodeling and complications of obesity. Methods: Wild type (WT) and TWEAK knockout (KO)...
8.
Defuria J, Belkina A, Jagannathan-Bogdan M, Snyder-Cappione J, Carr J, Nersesova Y, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(13):5133-8.
PMID: 23479618
Patients with type 2 diabetes (T2D) have disease-associated changes in B-cell function, but the role these changes play in disease pathogenesis is not well established. Data herein show B cells...
9.
Vieira Potter V, Strissel K, Xie C, Chang E, Bennett G, Defuria J, et al.
Endocrinology
. 2012 Jul;
153(9):4266-77.
PMID: 22778213
Menopause promotes central obesity, adipose tissue (AT) inflammation, and insulin resistance (IR). Both obesity and the loss of estrogen can activate innate and adaptive immune cells (macrophages, T cells). The...
10.
Strissel K, Defuria J, Shaul M, Bennett G, Greenberg A, Obin M
Obesity (Silver Spring)
. 2010 Jan;
18(10):1918-25.
PMID: 20111012
The role of adaptive immunity in obesity-associated adipose tissue (AT) inflammation and insulin resistance (IR) is controversial. We employed flow cytometry and quantitative PCR to assess T-cell recruitment and activation...