Jason De Meese
Overview
Explore the profile of Jason De Meese including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
15
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0
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Recent Articles
1.
Evans M, Smith D, Kress A, Nadeau R, Selig D, Caridha D, et al.
Clin Transl Sci
. 2024 Jul;
17(7):e13876.
PMID: 38963161
Plerixafor is a CXCR4 antagonist approved in 2008 by the FDA for hematopoietic stem cell collection. Subsequently, plerixafor has shown promise as a potential pathogen-agnostic immunomodulator in a variety of...
2.
Blake J, Gaudino J, De Meese J, Mohr P, Chicarelli M, Tian H, et al.
Bioorg Med Chem Lett
. 2014 May;
24(12):2635-9.
PMID: 24813737
The discovery and optimization of a series of tetrahydropyridopyrimidine based extracellular signal-regulated kinase (Erks) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent and...
3.
Le Huerou Y, Gunawardana I, Thomas A, Boyd S, De Meese J, DeWolf W, et al.
Bioorg Med Chem Lett
. 2007 Dec;
18(2):505-8.
PMID: 18083562
Transketolase, a key enzyme in the pentose phosphate pathway, has been suggested as a target for inhibition in the treatment of cancer. Compound 5a ('N3'-pyridyl thiamine'; 3-(6-methyl-2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride hydrochloride), an...