Jason D Williams
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Explore the profile of Jason D Williams including associated specialties, affiliations and a list of published articles.
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53
Citations
228
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Recent Articles
1.
Horch A, Williams J, Terossi M
Zool Stud
. 2024 Dec;
62:e13.
PMID: 39659813
A new species of Chopra, 1923, a parasitic isopod genus of the family Bopyridae found parasitizing two species of the snapping-shrimp genus Spence Bate, 1888, is described from Brazil. This...
2.
Boyko C, Williams J, Sancetta G
Syst Parasitol
. 2024 Oct;
101(6):70.
PMID: 39453505
The epicaridean isopods previously known to have epicaridium larvae with posterior yolk sacs were species of Pleurocryptella Bonnier, 1900 and a new subfamily, Pleurocryptellinae, was recently erected for this genus....
3.
An Automated Electrochemical Flow Platform to Accelerate Library Synthesis and Reaction Optimization
Rial-Rodriguez E, Williams J, Cantillo D, Fuchss T, Sommer A, Eggenweiler H, et al.
Angew Chem Int Ed Engl
. 2024 Sep;
63(51):e202412045.
PMID: 39317660
Automated batch and flow setups are well-established for high throughput experimentation in both thermal chemistry and photochemistry. However, the development of automated electrochemical platforms is hindered by cell miniaturization challenges...
4.
Saraf I, Jakasanovski O, Stanic T, Kralj E, Petek B, Williams J, et al.
Mol Pharm
. 2024 Sep;
21(11):5703-5715.
PMID: 39265053
Hot-melt extrusion (HME) is a widely used method for creating amorphous solid dispersions (ASDs) of poorly soluble drug substances, where the drug is molecularly dispersed in a solid polymer matrix....
5.
Sosa S, Brandt A, Chen C, Engel L, Esquete P, Horton T, et al.
Biodivers Data J
. 2024 Aug;
12:e128431.
PMID: 39171079
Background: Discoveries of new species often depend on one or a few specimens, leading to delays as researchers wait for additional context, sometimes for decades. There is currently little professional...
6.
Sagmeister P, Melnizky L, Williams J, Kappe C
Chem Sci
. 2024 Aug;
15(31):12523-12533.
PMID: 39118626
In modern pharmaceutical research, the demand for expeditious development of synthetic routes to active pharmaceutical ingredients (APIs) has led to a paradigm shift towards data-rich process development. Conventional methodologies encompass...
7.
Wagner F, Sagmeister P, Jusner C, Tampone T, Manee V, Buono F, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(13):e2308034.
PMID: 38273711
Flow processing offers many opportunities to optimize reactions in a rapid and automated manner, yet often requires relatively large quantities of input materials. To combat this, the use of a...
8.
Sagmeister P, Williams J, Kappe C
Chimia (Aarau)
. 2023 Dec;
77(5):300-306.
PMID: 38047825
The pharmaceutical industry has begun incorporating continuous manufacturing technology in synthetic routes toward active pharmaceutical ingredients (APIs). The development of smart manufacturing routes can be accelerated by utilizing digitalization, process...
9.
Prieschl M, Sedelmeier J, Puntener K, Hildbrand S, Williams J, Kappe C
J Org Chem
. 2023 Jun;
88(13):9594-9598.
PMID: 37339330
The expeditious synthesis of an API building block, 2-cyanothiazole, from cyanogen gas and a readily available dithiane is reported. A previously undisclosed partially saturated intermediate is formed, which can be...
10.
Beidleman B, Figueiredo P, Landspurg S, Femling J, Williams J, Staab J, et al.
J Appl Physiol (1985)
. 2023 Jun;
135(2):436-444.
PMID: 37318986
Acute mountain sickness (AMS) typically peaks following the first night at high altitude (HA) and resolves over the next 2-3 days, but the impact of active ascent on AMS is...