Jason C Poole
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Explore the profile of Jason C Poole including associated specialties, affiliations and a list of published articles.
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12
Citations
505
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Recent Articles
1.
Visser W, de Jong H, Smit F, Shrivastava J, Poole J, Leenders W, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39595976
Microarray and Single-Molecule Molecular Inversion Probe (smMIP)-based targeted RNA sequencing are two RNA profiling platforms for identifying disease-associated biomarkers. The microarray uses a GeneChip array with oligonucleotide probes to measure...
2.
Poole J, Wu S, Lu T, Vibat C, Pham A, Samuelsz E, et al.
PLoS One
. 2019 Oct;
14(10):e0223112.
PMID: 31581267
Background: Personalized medicine requires accurate molecular profiling for targeted therapy decisions. Insufficient tissue yield or tumor heterogeneity frequently limits the correct tissue biomarker determination. As a noninvasive complement to traditional...
3.
Hyman D, Diamond E, Vibat C, Hassaine L, Poole J, Patel M, et al.
Cancer Discov
. 2014 Oct;
5(1):64-71.
PMID: 25324352
Unlabelled: Patients with Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) have a high frequency of BRAF(V600E) mutations and respond to RAF inhibitors. However, detection of mutations in tissue biopsies...
4.
Lacovara K, Lamanna M, Ibiricu L, Poole J, Schroeter E, Ullmann P, et al.
Sci Rep
. 2014 Sep;
4:6196.
PMID: 25186586
Titanosaurian sauropod dinosaurs were the most diverse and abundant large-bodied herbivores in the southern continents during the final 30 million years of the Mesozoic Era. Several titanosaur species are regarded...
5.
Janku F, Vibat C, Kosco K, Holley V, Cabrilo G, Meric-Bernstam F, et al.
Oncotarget
. 2014 Jul;
5(11):3607-10.
PMID: 25003820
Erdheim-Chester disease (ECD) is a rare histiocytosis with a high prevalence of BRAF V600E mutation (>50% of patients). Patients with BRAF-mutant ECD can respond to BRAF inhibitors. Unfortunately, the lack...
6.
Poole J, Procaccio V, Brandon M, Merrick G, Wallace D
Biol Chem
. 2010 Aug;
391(10):1115-30.
PMID: 20707610
The mitochondrial DNA (mtDNA) encompasses two classes of functionally important sequence variants: recent pathogenic mutations and ancient adaptive polymorphisms. To rapidly and cheaply evaluate both classes of single nucleotide variants...
7.
Hendrickson S, Kingsley L, Ruiz-Pesini E, Poole J, Jacobson L, Palella F, et al.
J Acquir Immune Defic Syndr
. 2009 Apr;
51(2):111-6.
PMID: 19339895
Although highly active antiretroviral therapy (HAART) has been extremely effective in lowering AIDS incidence among patients infected with HIV, certain drugs included in HAART can cause serious mitochondrial toxicities. One...
8.
Hendrickson S, Hutcheson H, Ruiz-Pesini E, Poole J, Lautenberger J, Sezgin E, et al.
AIDS
. 2008 Nov;
22(18):2429-39.
PMID: 19005266
Objective: Mitochondrial function plays a role in both AIDS progression and HAART toxicity; therefore, we sought to determine whether mitochondrial DNA variation revealed novel AIDS restriction genes, particularly as mitochondrial...
9.
Ruiz-Pesini E, Lott M, Procaccio V, Poole J, Brandon M, Mishmar D, et al.
Nucleic Acids Res
. 2006 Dec;
35(Database issue):D823-8.
PMID: 17178747
The MITOMAP (http://www.mitomap.org) data system for the human mitochondrial genome has been greatly enhanced by the addition of a navigable mutational mitochondrial DNA (mtDNA) phylogenetic tree of approximately 3000 mtDNA...
10.
Procaccio V, Neckelmann N, Paquis-Flucklinger V, Bannwarth S, Jimenez R, Davila A, et al.
Mol Diagn Ther
. 2006 Dec;
10(6):381-9.
PMID: 17154655
Background: Mutations in the human mitochondrial genome have been suspected to play a significant role in the etiological development of mitochondrial diabetes. Detection of the 3243A>G mutation in the mitochondrial...