Jason C Maynard
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Explore the profile of Jason C Maynard including associated specialties, affiliations and a list of published articles.
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19
Citations
514
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Recent Articles
1.
Zhang Z, Huang Z, Awad M, Elsalanty M, Cray J, Ball L, et al.
Elife
. 2023 Mar;
12.
PMID: 36861967
In mammals, interactions between the bone marrow (BM) stroma and hematopoietic progenitors contribute to bone-BM homeostasis. Perinatal bone growth and ossification provide a microenvironment for the transition to definitive hematopoiesis;...
2.
Bi Y, Shrestha R, Zhang Z, Hsu C, Reyes A, Karunadasa S, et al.
Plant Cell
. 2023 Feb;
35(5):1318-1333.
PMID: 36739885
The recent discovery of SPINDLY (SPY)-catalyzed protein O-fucosylation revealed a novel mechanism for regulating nucleocytoplasmic protein functions in plants. Genetic evidence indicates the important roles of SPY in diverse developmental...
3.
Zhao M, Ren K, Xiong X, Xin Y, Zou Y, Maynard J, et al.
Immunity
. 2022 Jul;
55(7):1327.
PMID: 35830826
No abstract available.
4.
Zhao M, Ren K, Xiong X, Xin Y, Zou Y, Maynard J, et al.
Immunity
. 2022 Apr;
55(4):623-638.e5.
PMID: 35385697
The epithelium is an integral component of mucosal barrier and host immunity. Following helminth infection, the intestinal epithelial cells secrete "alarmin" cytokines, such as interleukin-25 (IL-25) and IL-33, to initiate...
5.
Mohan S, Sampognaro P, Argouarch A, Maynard J, Welch M, Patwardhan A, et al.
Mol Neurodegener
. 2021 Aug;
16(1):51.
PMID: 34344440
Background: Progranulin loss-of-function mutations are linked to frontotemporal lobar degeneration with TDP-43 positive inclusions (FTLD-TDP-Pgrn). Progranulin (PGRN) is an intracellular and secreted pro-protein that is proteolytically cleaved into individual granulin...
6.
Maynard J, Chalkley R
Mol Cell Proteomics
. 2020 Sep;
20:100031.
PMID: 32938750
O-GlcNAcylation, the addition of a single N-acetylglucosamine residue to serine and threonine residues of cytoplasmic, nuclear, or mitochondrial proteins, is a widespread regulatory posttranslational modification. It is involved in the...
7.
White 3rd C, Fan X, Maynard J, Wheatley E, Bieri G, Couthouis J, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(36):22214-22224.
PMID: 32848054
Increased neural stem cell (NSC) quiescence is a major determinant of age-related regenerative decline in the adult hippocampus. However, a coextensive model has been proposed in which division-coupled conversion of...
8.
Maynard J, Fujihira H, Dolgonos G, Suzuki T, Burlingame A
Biochem Biophys Res Commun
. 2020 Aug;
530(4):719-724.
PMID: 32782141
NGLY1 is a widely conserved eukaryotic cytosolic deglycosylating enzyme involved in the endoplasmic reticulum-associated degradation (ERAD) process, which eliminates misfolded proteins through retrograde translocation and proteasomal degradation. A human genetic...
9.
Liu B, Salgado O, Singh S, Hippen K, Maynard J, Burlingame A, et al.
Nat Commun
. 2019 Jan;
10(1):354.
PMID: 30664665
Regulatory T (Treg) cells control self-tolerance, inflammatory responses and tissue homeostasis. In mature Treg cells, continued expression of FOXP3 maintains lineage identity, while T cell receptor (TCR) signaling and interleukin-2...
10.
Kim S, Maynard J, Strickland A, Burlingame A, Milbrandt J
Proc Natl Acad Sci U S A
. 2018 Jul;
115(31):8019-8024.
PMID: 30012597
Schwann cells (SCs), the glia of the peripheral nervous system, play an essential role in nerve regeneration. Upon nerve injury, SCs are reprogrammed into unique "repair SCs," and these cells...