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Jason Bielas

Explore the profile of Jason Bielas including associated specialties, affiliations and a list of published articles. Areas
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Citations 29
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Recent Articles
1.
Asano Y, Veatch J, McAfee M, Bakhtiari J, Lee B, Martin L, et al.
medRxiv . 2024 Jul; PMID: 39006423
Although immune check-point inhibitors (CPIs) revolutionized treatment of Merkel cell carcinoma (MCC), patients with CPI-refractory MCC lack effective therapy. More than 80% of MCC express T-antigens encoded by Merkel cell...
2.
Lahman M, Schmitt T, Paulson K, Vigneron N, Buenrostro D, Wagener F, et al.
Sci Transl Med . 2022 Feb; 14(631):eabg8070. PMID: 35138909
Designing effective antileukemic immunotherapy will require understanding mechanisms underlying tumor control or resistance. Here, we report a mechanism of escape from immunologic targeting in an acute myeloid leukemia (AML) patient,...
3.
Bielas J, Herbst A, Widjaja K, Hui J, Aiken J, McKenzie D, et al.
Exp Gerontol . 2018 Feb; 106:125-131. PMID: 29486228
Age-induced mitochondrial DNA deletion mutations may underlie cell loss and tissue aging. Rapamycin extends mouse lifespan and modulates mitochondrial quality control. We hypothesized that reduced deletion mutation abundance may contribute...