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Aude G Chapuis

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Articles 39
Citations 1679
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Recent Articles
1.
Portuguese A, Huang J, Jeon Y, Taheri M, Albittar A, Liang E, et al.
Haematologica . 2025 Mar; PMID: 40079097
Lisocabtagene maraleucel (liso-cel) and axicabtagene ciloleucel (axi-cel) are FDA- and EMAapproved chimeric antigen receptor (CAR) T-cell therapies for relapsed/refractory large B-cell lymphoma (LBCL). However, comparative real-world analyses of their efficacy...
2.
Mazziotta F, Martin L, Eagan D, Bar M, Kinsella S, Paulson K, et al.
medRxiv . 2025 Jan; PMID: 39763516
Acute myeloid leukemia (AML) that is relapsed and/or refractory post-allogeneic hematopoietic cell transplantation (HCT) is usually fatal. In a prior study, we demonstrated that AML relapse in high-risk patients was...
3.
Liang E, Huang J, Portuguese A, Ortiz-Maldonado V, Albittar A, Wuliji N, et al.
Blood Adv . 2024 Dec; 9(3):606-616. PMID: 39626349
Immune effector cell-associated hematotoxicity (ICAHT) is associated with morbidity and mortality after chimeric antigen receptor (CAR) T-cell therapy. To date, the factors associated with ICAHT are poorly characterized, and there...
4.
Lee J, Chen E, Hu T, Perret R, Chaffee M, Martinov T, et al.
bioRxiv . 2024 Sep; PMID: 39345486
One-sentence Summary: Tumor cell methylation of KRAS epitope in HLA-A2 permits immune evasion, and new TCRs were generated to overcome this with engineered cell therapy.
5.
Ford E, Li A, Laing K, Dong L, Diem K, Jing L, et al.
JCI Insight . 2024 Aug; 9(14). PMID: 39133650
The skin at the site of HSV-2 reactivation is enriched for HSV-2-specific T cells. To evaluate whether an immunotherapeutic vaccine could elicit skin-based memory T cells, we studied skin biopsies...
6.
Asano Y, Veatch J, McAfee M, Bakhtiari J, Lee B, Martin L, et al.
medRxiv . 2024 Jul; PMID: 39006423
Although immune check-point inhibitors (CPIs) revolutionized treatment of Merkel cell carcinoma (MCC), patients with CPI-refractory MCC lack effective therapy. More than 80% of MCC express T-antigens encoded by Merkel cell...
7.
Pullarkat S, Black G, Bleakley M, Buenrostro D, Chapuis A, Hirayama A, et al.
PLoS One . 2024 Jun; 19(6):e0303057. PMID: 38843256
As adoptive cellular therapies become more commonplace in cancer care, there is a growing need to monitor site-specific localization of engineered cells-such as chimeric antigen receptor T (CAR-T) cells and...
8.
Cross D, Layton E, Yu K, Smith M, Aguilar M, Li S, et al.
JCI Insight . 2024 May; 9(9). PMID: 38716731
T cells are required for protective immunity against Mycobacterium tuberculosis. We recently described a cohort of Ugandan household contacts of tuberculosis cases who appear to "resist" M. tuberculosis infection (resisters;...
9.
Krakow E, Brault M, Summers C, Cunningham T, Biernacki M, Black R, et al.
Blood . 2024 Apr; 144(10):1069-1082. PMID: 38683966
Relapse is the leading cause of death after allogeneic hematopoietic stem cell transplantation (HCT) for leukemia. T cells engineered by gene transfer to express T cell receptors (TCR; TCR-T) specific...
10.
Ford E, Li A, Laing K, Dong L, Diem K, Jing L, et al.
medRxiv . 2024 Feb; PMID: 38352384
The skin at the site of HSV-2 reactivation is enriched for HSV-2-specific T cells. To evaluate whether an immunotherapeutic vaccine could elicit skin-based memory T cells, we studied skin biopsies...