Jason A Greenbaum
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Explore the profile of Jason A Greenbaum including associated specialties, affiliations and a list of published articles.
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9614
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Recent Articles
1.
Shinde P, Willemsen L, Anderson M, Aoki M, Basu S, Burel J, et al.
bioRxiv
. 2024 Sep;
PMID: 39282381
Systems vaccinology studies have been used to build computational models that predict individual vaccine responses and identify the factors contributing to differences in outcome. Comparing such models is challenging due...
2.
Richardson E, Trevizani R, Greenbaum J, Carter H, Nielsen M, Peters B
Patterns (N Y)
. 2024 Jul;
5(6):100994.
PMID: 39005487
Many problems in biology require looking for a "needle in a haystack," corresponding to a binary classification where there are a few positives within a much larger set of negatives,...
3.
Yan Z, Kim K, Kim H, Ha B, Gambiez A, Bennett J, et al.
Nucleic Acids Res
. 2024 May;
52(W1):W526-W532.
PMID: 38783079
The Next-Generation (NG) IEDB Tools website (https://nextgen-tools.iedb.org) provides users with a redesigned interface to many of the algorithms for epitope prediction and analysis that were originally released on the legacy...
4.
Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, et al.
Cell Rep Methods
. 2024 Mar;
4(3):100731.
PMID: 38490204
Systems vaccinology studies have identified factors affecting individual vaccine responses, but comparing these findings is challenging due to varying study designs. To address this lack of reproducibility, we established a...
5.
Brunel S, Picarda G, Gupta A, Ghosh R, McDonald B, El Morabiti R, et al.
PLoS Pathog
. 2024 Jan;
20(1):e1011852.
PMID: 38236791
Conventional antiviral memory CD4 T cells typically arise during the first two weeks of acute infection. Unlike most viruses, cytomegalovirus (CMV) exhibits an extended persistent replication phase followed by lifelong...
6.
Upadhye A, Meza Landeros K, Ramirez-Suastegui C, Schmiedel B, Woo E, Chee S, et al.
Nat Cancer
. 2024 Jan;
5(5):791-807.
PMID: 38228835
Brain tumors in children are a devastating disease in a high proportion of patients. Owing to inconsistent results in clinical trials in unstratified patients, the role of immunotherapy remains unclear....
7.
Marrama D, Chronister W, Westernberg L, Vita R, Kosaloglu-Yalcin Z, Sette A, et al.
BMC Bioinformatics
. 2023 Dec;
24(1):485.
PMID: 38110863
Background: Numerous tools exist for biological sequence comparisons and search. One case of particular interest for immunologists is finding matches for linear peptide T cell epitopes, typically between 8 and...
8.
Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, et al.
bioRxiv
. 2023 Sep;
PMID: 37693565
Computational models that predict an individual's response to a vaccine offer the potential for mechanistic insights and personalized vaccination strategies. These models are increasingly derived from systems vaccinology studies that...
9.
Dolina J, Lee J, Brightman S, McArdle S, Hall S, Thota R, et al.
J Clin Invest
. 2023 Sep;
133(17).
PMID: 37655661
Therapeutic benefit to immune checkpoint blockade (ICB) is currently limited to the subset of cancers thought to possess a sufficient tumor mutational burden (TMB) to allow for the spontaneous recognition...
10.
Dolina J, Lee J, Brightman S, McArdle S, Hall S, Thota R, et al.
bioRxiv
. 2023 May;
PMID: 37205330
Therapeutic benefit to immune checkpoint blockade (ICB) is currently limited to the subset of cancers thought to possess a sufficient tumor mutational burden (TMB) to allow for the spontaneous recognition...