Jared Sterneckert
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Explore the profile of Jared Sterneckert including associated specialties, affiliations and a list of published articles.
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59
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3784
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Recent Articles
1.
Hutchings A, Hambrecht B, Veh A, Giridhar N, Zare A, Angerer C, et al.
Nat Commun
. 2024 Oct;
15(1):8622.
PMID: 39366938
Increasing evidence suggests an essential function for autophagy in unconventional protein secretion (UPS). However, despite its relevance for the secretion of aggregate-prone proteins, the mechanisms of secretory autophagy in neurons...
2.
Pal A, Grossmann D, Glass H, Zimyanin V, GuNTHER R, Catinozzi M, et al.
Life Sci Alliance
. 2024 May;
7(8).
PMID: 38760174
Amyotrophic lateral sclerosis (ALS) leads to death within 2-5 yr. Currently, available drugs only slightly prolong survival. We present novel insights into the pathophysiology of (SOD1)- and in particular (FUS)-ALS...
3.
Alfahel L, Gschwendtberger T, Kozareva V, Dumas L, Gibbs R, Kertser A, et al.
Cell Rep Med
. 2024 May;
5(5):101546.
PMID: 38703766
Mutations in SOD1 cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by motor neuron (MN) loss. We previously discovered that macrophage migration inhibitory factor (MIF), whose levels are extremely...
4.
Hartmann C, Anskat M, Ehrlich M, Sterneckert J, Pal A, Hermann A
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540253
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by the progressive loss of neurons mainly in the frontal and temporal lobes of the brain. Mutations (e.g., V337M, N297K) in the...
5.
Bhatia P, Bickle M, Agrawal A, Truss B, Nikolaidi A, Brockmann K, et al.
Biology (Basel)
. 2024 Jan;
13(1).
PMID: 38275734
The degeneration of axon terminals before the soma, referred to as "dying back", is a feature of Parkinson's disease (PD). Axonal assays are needed to model early PD pathogenesis as...
6.
Kour S, Fortuna T, Anderson E, Mawrie D, Bilstein J, Sivasubramanian R, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):11258-11276.
PMID: 37791873
Mutations in the Fused in Sarcoma (FUS) gene cause the familial and progressive form of amyotrophic lateral sclerosis (ALS). FUS is a nuclear RNA-binding protein involved in RNA processing and...
7.
Castillo Bautista C, Eismann K, Gentzel M, Pelucchi S, Mertens J, Walters H, et al.
Cells
. 2023 Sep;
12(18).
PMID: 37759469
Aging is associated with the disruption of protein homeostasis and causally contributes to multiple diseases, including amyotrophic lateral sclerosis (ALS). One strategy for restoring protein homeostasis and protecting neurons against...
8.
Bhatia P, Sterneckert J
Signal Transduct Target Ther
. 2023 Sep;
8(1):362.
PMID: 37743375
No abstract available.
9.
Antoniani F, Cimino M, Mediani L, Vinet J, Verde E, Secco V, et al.
Cell Death Discov
. 2023 Jul;
9(1):248.
PMID: 37454169
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two neurodegenerative disorders that share genetic causes and pathogenic mechanisms. The critical genetic players of ALS and FTD are the TARDBP,...
10.
Zimyanin V, Pielka A, Glass H, Japtok J, Grossmann D, Martin M, et al.
Cells
. 2023 Jul;
12(10).
PMID: 37408187
Motoneurons are one of the most energy-demanding cell types and a primary target in Amyotrophic lateral sclerosis (ALS), a debilitating and lethal neurodegenerative disorder without currently available effective treatments. Disruption...