Jared S Fowles
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Explore the profile of Jared S Fowles including associated specialties, affiliations and a list of published articles.
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13
Citations
190
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Recent Articles
1.
Kong T, Laranjeira A, Letson C, Yu L, Lin S, Fowles J, et al.
Nat Commun
. 2025 Jan;
16(1):492.
PMID: 39820365
Myeloid malignancies are heterogenous disorders characterized by distinct molecular drivers but share convergence of oncogenic signaling pathways and propagation by ripe pro-inflammatory niches. Here, we establish a comprehensive transcriptional atlas...
2.
Flaig T, Tangen C, Daneshmand S, Alva A, Lucia M, McConkey D, et al.
Eur Urol
. 2023 Jul;
84(3):341-347.
PMID: 37414705
Background: The COXEN gene expression model was evaluated for prediction of response to neoadjuvant chemotherapy for muscle-invasive bladder cancer (MIBC). Objective: To conduct a secondary analysis of the association of...
3.
Kong T, Laranjeira A, Yang K, Fisher D, Yu L, Poittevin De La Fregonniere L, et al.
Nat Cancer
. 2022 Dec;
4(1):108-127.
PMID: 36581736
Myeloproliferative neoplasms (MPNs) exhibit a propensity for transformation to secondary acute myeloid leukemia (sAML), for which the underlying mechanisms remain poorly understood, resulting in limited treatment options and dismal clinical...
4.
Abegglen L, Harrison T, Moresco A, Fowles J, Troan B, Kiso W, et al.
Animals (Basel)
. 2022 Aug;
12(15).
PMID: 35953994
Reproductive tumors can impact conception, pregnancy, and birth in mammals. These impacts are well documented in humans, while data in other mammals are limited. An urgent need exists to understand...
5.
Zhou A, Kong T, Fowles J, Jung C, Allen M, Fisher D, et al.
Br J Haematol
. 2022 Feb;
197(4):e49-e52.
PMID: 35128632
No abstract available.
6.
Das S, Idate R, Regan D, Fowles J, Lana S, Thamm D, et al.
Commun Biol
. 2021 Oct;
4(1):1178.
PMID: 34635775
Osteosarcoma affects about 2.8% of dogs with cancer, with a one-year survival rate of approximately 45%. The purpose of this study was to characterize mutation and expression profiles of osteosarcoma...
7.
Gustafson D, Collins K, Fowles J, Ehrhart E, Weishaar K, Das S, et al.
Cancer Chemother Pharmacol
. 2021 Jul;
88(4):699-712.
PMID: 34263337
Background: This study is a prospective clinical trial in dogs with osteosarcoma testing a gene expression model (GEM) predicting the chemosensitivity of tumors to carboplatin (CARBO) or doxorubicin (DOX) developed...
8.
Celik H, Krug E, Zhang C, Han W, Issa N, Koh W, et al.
Cancer Discov
. 2021 Jul;
11(12):3126-3141.
PMID: 34193440
Significance: Although the genetic events driving MPNs are well defined, therapeutic discovery has been hampered by the inability of murine models to replicate key patient pathologies. Here, we present a...
9.
Liu R, Gao Q, Foltz S, Fowles J, Yao L, Wang J, et al.
Nat Commun
. 2021 May;
12(1):2559.
PMID: 33963182
Multiple myeloma (MM) is characterized by the uncontrolled proliferation of plasma cells. Despite recent treatment advances, it is still incurable as disease progression is not fully understood. To investigate MM...
10.
Flaig T, Tangen C, Daneshmand S, Alva A, Lerner S, Lucia M, et al.
Clin Cancer Res
. 2021 Feb;
27(9):2435-2441.
PMID: 33568346
Purpose: Dose-dense methotrexate-vinblastine-adriamycin-cisplatin (ddMVAC) and gemcitabine-cisplatin (GC) are accepted neoadjuvant regimens for muscle-invasive bladder cancer. The aim of this study was to validate the score from a coexpression extrapolation (COXEN)...