Jared L Johnson
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Explore the profile of Jared L Johnson including associated specialties, affiliations and a list of published articles.
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49
Citations
1610
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Recent Articles
1.
Horne C, Dite T, Young S, Mather L, Dagley L, Johnson J, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(8):e2420961122.
PMID: 39964718
Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung, and kidney cancers. However, little is known about PSKH1...
2.
OBoyle B, Yeung W, Lu J, Katiyar S, Yaron-Barir T, Johnson J, et al.
bioRxiv
. 2025 Jan;
PMID: 39868133
Bacterial serine-threonine protein kinases (STKs) regulate diverse cellular processes associated with cell growth, virulence, and pathogenicity. They are evolutionarily related to the druggable eukaryotic STKs. However, an incomplete knowledge of...
3.
Jun H, Paulo J, Appleman V, Yaron-Barir T, Johnson J, Yeo A, et al.
iScience
. 2024 Dec;
27(12):111278.
PMID: 39660053
PTEN plays a crucial role in preventing the development of glioblastoma (GBM), a severe and untreatable brain cancer. In GBM, most PTEN deficiencies are missense mutations that have not been...
4.
Hillis A, Tamir T, Perry G, Asara J, Johnson J, Yaron T, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2413837121.
PMID: 39536083
Tyrosine phosphorylation of metabolic enzymes is an evolutionarily conserved posttranslational modification that facilitates rapid and reversible modulation of enzyme activity, localization, or function. Despite the high abundance of tyrosine phosphorylation...
5.
Wu Y, Foollee A, Chan A, Hille S, Hauke J, Challis M, et al.
Nat Commun
. 2024 Sep;
15(1):8390.
PMID: 39333498
The peptide hormone glucagon is a fundamental metabolic regulator that is also being considered as a pharmacotherapeutic option for obesity and type 2 diabetes. Despite this, we know very little...
6.
Liu J, Cao S, Imbach K, Gritsenko M, Lih T, Kyle J, et al.
Cancer Cell
. 2024 Jul;
42(7):1217-1238.e19.
PMID: 38981438
Although genomic anomalies in glioblastoma (GBM) have been well studied for over a decade, its 5-year survival rate remains lower than 5%. We seek to expand the molecular landscape of...
7.
Gassaway B, Huttlin E, Huntsman E, Yaron-Barir T, Johnson J, Kurmi K, et al.
Mol Cell Proteomics
. 2024 Jun;
23(7):100801.
PMID: 38880243
T cell activation is a complex biological process of naive cells maturing into effector cells. Proteomic and phospho-proteomic approaches have provided critical insights into this process, yet it is not...
8.
Sinha N, McKenney C, Yeow Z, Li J, Nam K, Yaron-Barir T, et al.
Cell
. 2024 Jun;
187(14):3652-3670.e40.
PMID: 38843833
While ultraviolet (UV) radiation damages DNA, eliciting the DNA damage response (DDR), it also damages RNA, triggering transcriptome-wide ribosomal collisions and eliciting a ribotoxic stress response (RSR). However, the relative...
9.
Klomp J, Diehl J, Klomp J, Edwards A, Yang R, Morales A, et al.
Science
. 2024 Jun;
384(6700):eadk0850.
PMID: 38843329
To delineate the mechanisms by which the ERK1 and ERK2 mitogen-activated protein kinases support mutant KRAS-driven cancer growth, we determined the ERK-dependent phosphoproteome in KRAS-mutant pancreatic cancer. We determined that...
10.
Han Y, Duan X, Yang L, Nilsson-Payant B, Wang P, Duan F, et al.
Nature
. 2024 May;
630(8016):E7.
PMID: 38811742
No abstract available.