Jared K Nelson
Overview
Explore the profile of Jared K Nelson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
68
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Nelson J, Burns C, Smith M, Twamley B, Natale N
Tetrahedron Lett
. 2010 Nov;
49(19):3078-3082.
PMID: 21103024
The lithio-anion of isoxazole 2 was found to ring open propylene oxide in good yields with complete regioselectivity. Vinylic and benzylic epoxides were utilized as key examples of electrophiles and...
2.
Patel S, Rajale T, OBrien E, Burkhart D, Nelson J, Twamley B, et al.
Bioorg Med Chem
. 2009 Nov;
18(1):202-13.
PMID: 19932968
Analogues of amino methylisoxazole propionic acid (AMPA), were prepared from a common intermediate 12, including lipophilic analogues using lateral metalation and electrophilic quenching, and were evaluated at System xc-. Both...
3.
Nelson J, Twamley B, Villalobos T, Natale N
Tetrahedron Lett
. 2009 Oct;
49(41):5957-5960.
PMID: 19812681
Nucleophilic addition of alkyl- and aryl zinc reagents to a C(4) functionalized isoxazolyl aldehyde proceeded effectively with high enantioselectivity (85-94% e.e.). The amino alcohol catalyst (S)-2-piperidinyl-1,1,2-triphenyl ethanol (10) afforded the...
4.
Nelson J, Frolund S, Tikhonov D, Kristensen A, Stromgaard K
Angew Chem Int Ed Engl
. 2009 Jan;
48(17):3087-91.
PMID: 19152392
More discerning than the parent: Analogues of the polyamine toxin argiotoxin 636 (shown docked in the ion channel of an ionotropic glutamate (iGlu) receptor; N blue, O red) distinguish subtypes...
5.
Yu Q, Nelson J, Zheng M, Jackson M, Powles S
Pest Manag Sci
. 2007 Aug;
63(9):918-27.
PMID: 17665369
Background: The acetolactate synthase (ALS)-inhibiting herbicide sulfosulfuron is registered in Australia for the selective control of Hordeum leporinum Link. in wheat crops. This herbicide failed to control H. leporinum on...
6.
Andersen T, Tikhonov D, Bolcho U, Bolshakov K, Nelson J, Pluteanu F, et al.
J Med Chem
. 2006 Sep;
49(18):5414-23.
PMID: 16942015
Philanthotoxins are uncompetitive antagonists of Ca2+-permeable AMPA receptors presumed to bind to the pore-forming region, but a detailed molecular mechanism for this interaction is missing. Here a small library of...
7.
Natale N, Magnusson K, Nelson J
Curr Top Med Chem
. 2006 May;
6(8):823-47.
PMID: 16719820
A major neurotransmitter, L-Glutamate must be stored, transported and received, and these processes are mediated by proteins that bind this simple yet essential amino acid. Detailed evidence continues to emerge...
8.
Burkhart D, McKenzie A, Nelson J, Myers K, Zhao X, Magnusson K, et al.
Org Lett
. 2004 Apr;
6(8):1285-8.
PMID: 15070318
Utilizing our lateral metalation coupled with Jacobsen's catalytic asymmetric amino nitrile synthesis, we have demonstrated the ability to synthesize isoxazole-containing amino acid glutamate analogues in high yield and high enantiomeric...
9.
Zamponi G, Stotz S, Staples R, Andro T, Nelson J, Hulubei V, et al.
J Med Chem
. 2002 Dec;
46(1):87-96.
PMID: 12502362
A series of 4-isoxazolyl-1,4-dihydropyridines (IDs) were prepared and characterized, and their interaction with the calcium channel was studied by patch clamp analysis. The structure-activity relationship (SAR) that emerges is distinct...