Jared Adolf-Bryfogle
Overview
Explore the profile of Jared Adolf-Bryfogle including associated specialties, affiliations and a list of published articles.
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27
Citations
968
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Recent Articles
1.
Colom M, Vucinic J, Adolf-Bryfogle J, Bowman J, Verel S, Moczygemba I, et al.
Protein Sci
. 2024 Jul;
33(8):e5109.
PMID: 38989563
Understanding how proteins evolve under selective pressure is a longstanding challenge. The immensity of the search space has limited efforts to systematically evaluate the impact of multiple simultaneous mutations, so...
2.
Adolf-Bryfogle J, Labonte J, Kraft J, Shapovalov M, Raemisch S, Lutteke T, et al.
PLoS Comput Biol
. 2024 Jun;
20(6):e1011895.
PMID: 38913746
Carbohydrates and glycoproteins modulate key biological functions. However, experimental structure determination of sugar polymers is notoriously difficult. Computational approaches can aid in carbohydrate structure prediction, structure determination, and design. In...
3.
Wang Z, Brand R, Adolf-Bryfogle J, Grewal J, Qi Y, Combs S, et al.
ACS Omega
. 2024 Feb;
9(7):7471-7479.
PMID: 38405499
Computational prediction of molecule-protein interactions has been key for developing new molecules to interact with a target protein for therapeutics development. Previous work includes two independent streams of approaches: (1)...
4.
Hernandez N, Jankowski W, Frick R, Kelow S, Lubin J, Simhadri V, et al.
Heliyon
. 2023 Sep;
9(8):e17901.
PMID: 37701412
[This corrects the article DOI: 10.1016/j.heliyon.2023.e15032.].
5.
Hernandez N, Jankowski W, Frick R, Kelow S, Lubin J, Simhadri V, et al.
Heliyon
. 2023 Apr;
9(4):e15032.
PMID: 37035348
The human infectious disease COVID-19 caused by the SARS-CoV-2 virus has become a major threat to global public health. Developing a vaccine is the preferred prophylactic response to epidemics and...
6.
Colom M, Vucinic J, Adolf-Bryfogle J, Bowman J, Verel S, Moczygemba I, et al.
Res Sq
. 2022 Dec;
PMID: 36482980
Understanding how proteins evolve under selective pressure is a longstanding challenge. The immensity of the search space has limited efforts to systematically evaluate the impact of multiple simultaneous mutations, so...
7.
Le K, Adolf-Bryfogle J, Klima J, Lyskov S, Labonte J, Bertolani S, et al.
Biophysicist (Rockv)
. 2022 Feb;
2(1):108-122.
PMID: 35128343
Biomolecular structure drives function, and computational capabilities have progressed such that the prediction and computational design of biomolecular structures is increasingly feasible. Because computational biophysics attracts students from many different...
8.
Konrath K, Liaw K, Wu Y, Zhu X, Walker S, Xu Z, et al.
Cell Rep
. 2022 Jan;
38(5):110318.
PMID: 35090597
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines may target epitopes that reduce durability or increase the potential for escape from vaccine-induced immunity. Using synthetic vaccinology, we have developed rationally...
9.
Jeong B, Cha J, Hwang I, Kim U, Adolf-Bryfogle J, Coventry B, et al.
MAbs
. 2022 Jan;
14(1):2021601.
PMID: 35030983
Coronavirus disease 2019, caused by SARS-CoV-2, remains an on-going pandemic, partly due to the emergence of variant viruses that can "break-through" the protection of the current vaccines and neutralizing antibodies...
10.
Leman J, Lyskov S, Lewis S, Adolf-Bryfogle J, Alford R, Barlow K, et al.
Nat Commun
. 2021 Nov;
12(1):6947.
PMID: 34845212
Each year vast international resources are wasted on irreproducible research. The scientific community has been slow to adopt standard software engineering practices, despite the increases in high-dimensional data, complexities of...