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Janusz A Siedlecki

Explore the profile of Janusz A Siedlecki including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 773
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Recent Articles
1.
Sarnowska E, Kubala S, Cwiek P, Sacharowski S, Oksinska P, Steciuk J, et al.
Plant J . 2023 Apr; 115(3):788-802. PMID: 37114596
The Arabidopsis ERECTA family (ERf) of leucine-rich repeat receptor-like kinases (LRR-RLKs) comprising ERECTA (ER), ERECTA-LIKE 1 (ERL1), and ERECTA-LIKE 2 (ERL2) controls epidermal patterning, inflorescence architecture, and stomata development and...
2.
Szarkowska J, Cwiek P, Szymanski M, Rusetska N, Jancewicz I, Stachowiak M, et al.
Am J Cancer Res . 2022 Jan; 11(12):5965-5978. PMID: 35018236
About 40% of clear cell renal cell carcinoma (ccRCC) cases carry the mutation inactivating BAF180 subunit of the SWI/SNF chromatin remodeling complex (CRC). Here we show that the majority of...
3.
Jancewicz I, Szarkowska J, Konopinski R, Stachowiak M, Swiatek M, Blachnio K, et al.
Cancers (Basel) . 2021 Aug; 13(16). PMID: 34439305
Growing tumors avoid recognition and destruction by the immune system. During continuous stimulation of tumor-infiltrating lymphocytes (TILs) by tumors, TILs become functionally exhausted; thus, they become unable to kill tumor...
4.
Szymanski M, Rusetska N, Jancewicz I, Armatowska A, Ligaj M, Chrzan A, et al.
Oncologist . 2021 May; 26(9):e1652-e1655. PMID: 34003534
Succinate dehydrogenase (SDH)-deficient renal cancer is a rare renal cancer subtype recently accepted by the World Health Organization as a unique subtype of renal cell carcinoma (RCC). Here we report...
5.
Gos A, Rutkowski P, Siedlecki J
Methods Mol Biol . 2021 Mar; 2265:377-384. PMID: 33704728
We present the assay based on multimarker analysis of mRNA transcripts associated with melanocytic cells detected in lymphatic fluid collected after lymph node dissection. Positive results of reverse transcriptase polymerase...
6.
Bujko M, Kober P, Boresowicz J, Rusetska N, Zeber-Lubecka N, Paziewska A, et al.
J Clin Med . 2021 Jan; 10(3). PMID: 33498176
Background: mutations are the most common driver changes in corticotroph pituitary tumors. They have direct effect on cells' proteome through disturbance of ubiquitination process and also influence gene expression. The...
7.
Boresowicz J, Kober P, Rusetska N, Maksymowicz M, Paziewska A, Dabrowska M, et al.
Int J Endocrinol . 2020 Dec; 2020:3730657. PMID: 33354213
Purpose: Nonfunctioning gonadotropic pituitary neuroendocrine tumors (PitNETs) are among the most frequent neoplasms of pituitary gland. Although PitNETs are commonly considered benign, a notable part of patients suffer from tumor...
8.
Boresowicz J, Kober P, Rusetska N, Maksymowicz M, Paziewska A, Dabrowska M, et al.
Life (Basel) . 2020 May; 10(5). PMID: 32413978
microRNAs are involved in pathogenesis of cancer. DNA methylation plays a role in transcription of miRNA-encoding genes and may contribute to changed miRNA expression in tumors. This issue was not...
9.
Jagielska B, Ozdowska P, Gepner K, Kubala S, Siedlecki J, Sarnowski T, et al.
IUBMB Life . 2020 May; 72(6):1160-1167. PMID: 32359132
Immunotherapy based on immune checkpoint inhibitors (ICIs) is currently broadly used in the treatment of different types of cancer. The treatment targeting programmed cell death protein 1/programmed death-ligand 1 axis...
10.
Swiatek M, Jancewicz I, Kluebsoongnoen J, Zub R, Maassen A, Kubala S, et al.
IUBMB Life . 2020 Apr; 72(6):1220-1232. PMID: 32250548
Renal cell carcinoma (RCC) represents around 2-3% of all malignancies diagnosed in adult patients. Most frequent (around 70-80% cases) and the most aggressive subtype is clear cell RCC (ccRCC). Mutations...