January T Salas
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Explore the profile of January T Salas including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
331
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Recent Articles
1.
Concepcion A, Salas J, Saez E, Sarvide S, Ferrer A, Portu A, et al.
Oncotarget
. 2015 Sep;
6(30):28588-606.
PMID: 26396175
Unlabelled: Primary biliary cirrhosis (PBC) is a chronic cholestatic disease of unknown etiopathogenesis showing progressive autoimmune-mediated cholangitis. In PBC patients, the liver and lymphocytes exhibit diminished expression of AE2/SLC4A2, a...
2.
Lipson E, Sharfman W, Chen S, McMiller T, Pritchard T, Salas J, et al.
J Transl Med
. 2015 Jul;
13:214.
PMID: 26143264
Background: Limited adjuvant treatment options exist for patients with high-risk surgically resected melanoma. This first-in-human study investigated the safety, tolerability and immunologic correlates of Melanoma GVAX, a lethally irradiated granulocyte-macrophage...
3.
Taube J, Young G, McMiller T, Chen S, Salas J, Pritchard T, et al.
Clin Cancer Res
. 2015 May;
21(17):3969-76.
PMID: 25944800
Purpose: Blocking the immunosuppressive PD-1/PD-L1 pathway has antitumor activity in multiple cancer types, and PD-L1 expression on tumor cells and infiltrating myeloid cells correlates with the likelihood of response. We...
4.
Salas J, Chang T
Clin Lab Med
. 2014 Dec;
34(4):733-45.
PMID: 25439273
Human immunodeficiency virus (HIV) primary infection occurs at mucosa tissues, suggesting an intricate interplay between the microbiome and HIV infection. Recent advanced technologies of high-throughput sequencing and bioinformatics allow researchers...
5.
Concepcion A, Salas J, Sarvide S, Saez E, Ferrer A, Lopez M, et al.
Eur J Immunol
. 2014 Feb;
44(5):1341-51.
PMID: 24515893
Mitogenic stimulation of lymphocytes involves alkalinization of intracellular pH (pHi ). Subsequent pHi regulation may involve HCO3 (-) extrusion through Cl(-) /HCO3 (-) exchangers and/or Na(+) -HCO3 (-) co-transporters with...
6.
Salas J, Banales J, Sarvide S, Recalde S, Ferrer A, Uriarte I, et al.
Gastroenterology
. 2008 May;
134(5):1482-93.
PMID: 18471521
Background & Aims: Cl(-)/HCO(3)(-) anion exchanger 2 (AE2) is involved in intracellular pH (pH(i)) regulation and transepithelial acid-base transport, including secretin-stimulated biliary bicarbonate excretion. AE2 gene expression was found to...
7.
Recalde S, Muruzabal F, Looije N, Kunne C, Burrell M, Saez E, et al.
Am J Pathol
. 2006 Jul;
169(1):165-76.
PMID: 16816370
In parietal cells, basolateral Ae2 Cl(-)/HCO(3)(-) exchanger (Slc4a2) appears to compensate for luminal H(+) pumping while providing Cl(-) for apical secretion. In mouse and rat, mRNA variants Ae2a, Ae2b1, Ae2b2,...