Janny van den Burg
Overview
Explore the profile of Janny van den Burg including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
258
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Recent Articles
1.
Clemente-Olivo M, Hernandez-Quiles M, Sparrius R, van der Stoel M, Janssen V, Habibe J, et al.
Cell Signal
. 2023 Jan;
104:110587.
PMID: 36610523
The LIM-domain-only protein FHL2 is a modulator of signal transduction and has been shown to direct the differentiation of mesenchymal stem cells towards osteoblast and myocyte phenotypes. We hypothesized that...
2.
Bossuyt S, Punt A, de Graaf I, van den Burg J, Williams M, Heussler H, et al.
Hum Mol Genet
. 2021 Feb;
30(6):430-442.
PMID: 33607653
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by deletion (~75%) or mutation (~10%) of the ubiquitin E3 ligase A (UBE3A) gene, which encodes a HECT type E3 ubiquitin...
3.
Avagliano Trezza R, van den Burg J, van den Oever N, Distel B
Microb Cell
. 2018 Mar;
5(3):150-157.
PMID: 29487861
Ubiquitination is a posttranslational protein modification that regulates most aspects of cellular life. The sheer number of ubiquitination enzymes that are present in a mammalian cell, over 700 in total,...
4.
Gkourtsa A, van den Burg J, Avula T, Hochstenbach F, Distel B
Microbiol Res
. 2016 Jul;
190:27-36.
PMID: 27393996
Src-homology 3 (SH3) domains are small protein-protein interaction modules. While most SH3 domains bind to proline-x-x-proline (PxxP) containing motifs in their binding partners, some SH3 domains recognize motifs other than...
5.
Gkourtsa A, van den Burg J, Strijbis K, Avula T, Bijvoets S, Timm D, et al.
Eukaryot Cell
. 2014 Dec;
14(2):182-93.
PMID: 25548150
Membrane reshaping resides at the core of many important cellular processes, and among its mediators are the BAR (Bin, Amphiphysin, Rvs) domain-containing proteins. We have explored the diversity and function...
6.
Strijbis K, van den Burg J, Visser W, van den Berg M, Distel B
FEMS Yeast Res
. 2011 Nov;
12(1):61-8.
PMID: 22094058
The pentose phosphate pathway (PPP) is the main source of NADPH in the cell and therefore essential for the maintenance of the redox balance and anabolic reactions. NADPH is produced...
7.
Strijbis K, van Roermund C, van den Burg J, van den Berg M, Hardy G, Wanders R, et al.
J Biol Chem
. 2010 Jun;
285(32):24335-46.
PMID: 20522553
Transport of acetyl-CoA between intracellular compartments is mediated by carnitine acetyltransferases (Cats) that reversibly link acetyl units to the carrier molecule carnitine. The genome of the opportunistic pathogenic yeast Candida...
8.
Identification and characterization of a complete carnitine biosynthesis pathway in Candida albicans
Strijbis K, van Roermund C, Hardy G, van den Burg J, Bloem K, de Haan J, et al.
FASEB J
. 2009 Mar;
23(8):2349-59.
PMID: 19289605
Carnitine is an essential metabolite that enables intracellular transport of fatty acids and acetyl units. Here we show that the yeast Candida albicans can synthesize carnitine de novo, and we...
9.
Piekarska K, Hardy G, Mol E, van den Burg J, Strijbis K, van Roermund C, et al.
Microbiology (Reading)
. 2008 Oct;
154(Pt 10):3061-3072.
PMID: 18832312
The glyoxylate cycle, a metabolic pathway required for generating C(4) units from C(2) compounds, is an important factor in virulence, in both animal and plant pathogens. Here, we report the...
10.
Strijbis K, van Roermund C, Visser W, Mol E, van den Burg J, MacCallum D, et al.
Eukaryot Cell
. 2008 Feb;
7(4):610-8.
PMID: 18281597
In eukaryotes, acetyl coenzyme A (acetyl-CoA) produced during peroxisomal fatty acid beta-oxidation needs to be transported to mitochondria for further metabolism. Two parallel pathways for acetyl-CoA transport have been identified...