Janna Luessing
Overview
Explore the profile of Janna Luessing including associated specialties, affiliations and a list of published articles.
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6
Citations
39
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0
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Recent Articles
1.
Bader A, Luessing J, Hawley B, Skalka G, Lu W, Lowndes N, et al.
Nucleic Acids Res
. 2022 Oct;
50(18):10487-10502.
PMID: 36200807
Proteins with RNA-binding activity are increasingly being implicated in DNA damage responses (DDR). Additionally, DNA:RNA-hybrids are rapidly generated around DNA double-strand breaks (DSBs), and are essential for effective repair. Here,...
2.
Luessing J, Okowa C, Brennan E, Voisin M, Lowndes N
iScience
. 2022 Jun;
25(7):104536.
PMID: 35754741
Abscission, the final stage of cytokinesis, occurs when the cytoplasmic canal connecting two emerging daughter cells is severed either side of a large proteinaceous structure, the midbody. Here, we expand...
3.
Luessing J, Sakhteh M, Sarai N, Frizzell L, Tsanov N, Ramberg K, et al.
Cell Rep
. 2021 Jun;
35(13):109306.
PMID: 34192545
53BP1 is recruited to chromatin in the vicinity of DNA double-strand breaks (DSBs). We identify the nuclear kinesin, KIF18B, as a 53BP1-interacting protein and define its role in 53BP1-mediated DSB...
4.
Tabrizi L, Thompson K, Mnich K, Chintha C, Gorman A, Morrison L, et al.
Mol Pharm
. 2020 Jul;
17(8):3009-3023.
PMID: 32628022
The design, synthesis, characterization, and biological activity of a series of platinum(IV) prodrugs containing the axial ligand 3-(4-phenylquinazoline-2-carboxamido)propanoate () are reported. is a derivative of the quinazolinecarboxamide class of ligands...
5.
Llorens-Agost M, Luessing J, van Beneden A, Eykelenboom J, OReilly D, Bicknell L, et al.
Hum Mutat
. 2018 Sep;
39(12):1847-1853.
PMID: 30199583
Ataxia Telangiectasia and Rad3 related (ATR) is one of the main regulators of the DNA damage response. It coordinates cell cycle checkpoint activation, replication fork stability, restart and origin firing...
6.
Moureau S, Luessing J, Harte E, Voisin M, Lowndes N
Open Biol
. 2016 Sep;
6(9).
PMID: 27655732
Loss of p53, a transcription factor activated by cellular stress, is a frequent event in cancer. The role of p53 in tumour suppression is largely attributed to cell fate decisions....