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Janine Schniering

Explore the profile of Janine Schniering including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 493
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Recent Articles
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Luecken M, Zaragosi L, Madissoon E, Sikkema L, Firsova A, De Domenico E, et al.
Eur Respir J . 2022 Jan; 60(2). PMID: 35086829
The Human Cell Atlas (HCA) consortium aims to establish an atlas of all organs in the healthy human body at single-cell resolution to increase our understanding of basic biological processes...
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Lange M, Bergen V, Klein M, Setty M, Reuter B, Bakhti M, et al.
Nat Methods . 2022 Jan; 19(2):159-170. PMID: 35027767
Computational trajectory inference enables the reconstruction of cell state dynamics from single-cell RNA sequencing experiments. However, trajectory inference requires that the direction of a biological process is known, largely limiting...
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Schniering J, Maciukiewicz M, Gabrys H, Brunner M, Bluthgen C, Meier C, et al.
Eur Respir J . 2021 Oct; 59(5). PMID: 34649979
Background: Radiomic features calculated from routine medical images show great potential for personalised medicine in cancer. Patients with systemic sclerosis (SSc), a rare, multiorgan autoimmune disorder, have a similarly poor...
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Rudnik M, Hukara A, Kocherova I, Jordan S, Schniering J, Milleret V, et al.
Front Immunol . 2021 Sep; 12:642891. PMID: 34504485
Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by overproduction of extracellular matrix (ECM) and multiorgan fibrosis. Animal studies pointed to bone marrow-derived cells as a potential source of...
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Yokota M, Haffner N, Kassier M, Brunner M, Mairpady Shambat S, Brennecke F, et al.
FASEB J . 2021 Jun; 35(7):e21695. PMID: 34160101
Chronic wounds are a major disease burden worldwide. The breach of the epithelial barrier facilitates transition of skin commensals to invasive facultative pathogens. Therefore, we investigated the potential effects of...
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Mayr C, Simon L, Leuschner G, Ansari M, Schniering J, Geyer P, et al.
EMBO Mol Med . 2021 Mar; 13(4):e12871. PMID: 33650774
The correspondence of cell state changes in diseased organs to peripheral protein signatures is currently unknown. Here, we generated and integrated single-cell transcriptomic and proteomic data from multiple large pulmonary...
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Denzler S, Vuong D, Bogowicz M, Pavic M, Frauenfelder T, Thierstein S, et al.
Br J Radiol . 2021 Feb; 94(1120):20200947. PMID: 33544646
Objectives: In this study, we aimed to assess the impact of different CT reconstruction kernels on the stability of radiomic features and the transferability between different diseases and tissue types....
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Pachera E, Assassi S, Salazar G, Stellato M, Renoux F, Wunderlin A, et al.
J Clin Invest . 2020 Jul; 130(9):4888-4905. PMID: 32603313
TGF-β is a master regulator of fibrosis, driving the differentiation of fibroblasts into apoptosis-resistant myofibroblasts and sustaining the production of extracellular matrix (ECM) components. Here, we identified the nuclear long...
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Schniering J, Benesova M, Brunner M, Haller S, Cohrs S, Frauenfelder T, et al.
Front Immunol . 2019 Dec; 10:2724. PMID: 31824505
Interstitial lung disease (ILD) is a common and severe complication in rheumatic diseases. Folate receptor-β is expressed on activated, but not resting macrophages which play a key role in dysregulated...