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Janine J G Arts

Explore the profile of Janine J G Arts including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 94
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Recent Articles
1.
Gronloh M, Tebbens M, Kotsi M, Arts J, van Buul J
Vasc Biol . 2023 Aug; 5(1). PMID: 37565726
Intercellular adhesion molecules (ICAMs) are cell surface proteins that play a crucial role in the body's immune response and inflammatory processes. ICAM1 and ICAM2 are two ICAM family members expressed...
2.
Mahlandt E, Palacios Martinez S, Arts J, Tol S, van Buul J, Goedhart J
Elife . 2023 Jul; 12. PMID: 37449837
The inner layer of blood vessels consists of endothelial cells, which form the physical barrier between blood and tissue. This vascular barrier is tightly regulated and is defined by cell-cell...
3.
Gronloh M, Arts J, Palacios Martinez S, van der Veen A, Kempers L, van Steen A, et al.
EMBO Rep . 2022 Nov; 24(1):e55483. PMID: 36382783
Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration "hotspot" regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that...
4.
van der Linden F, Mahlandt E, Arts J, Beumer J, Puschhof J, de Man S, et al.
Nat Commun . 2021 Dec; 12(1):7159. PMID: 34887382
The most successful genetically encoded calcium indicators (GECIs) employ an intensity or ratiometric readout. Despite a large calcium-dependent change in fluorescence intensity, the quantification of calcium concentrations with GECIs is...
5.
Mahlandt E, Arts J, van der Meer W, van der Linden F, Tol S, van Buul J, et al.
J Cell Sci . 2021 Aug; 134(17). PMID: 34357388
Rho GTPases are regulatory proteins, which orchestrate cell features such as morphology, polarity and movement. Therefore, probing Rho GTPase activity is key to understanding processes such as development and cell...
6.
Arts J, Mahlandt E, Schimmel L, Gronloh M, Niet S, Klein B, et al.
Front Immunol . 2021 Jun; 12:667213. PMID: 34084168
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on...
7.
Gronloh M, Arts J, van Buul J
J Cell Sci . 2021 Apr; 134(7). PMID: 33795378
During inflammation, leukocytes circulating in the blood stream exit the vasculature in a process called leukocyte transendothelial migration (TEM). The current paradigm of this process comprises several well-established steps, including...