» Authors » Janet M Wenzlau

Janet M Wenzlau

Explore the profile of Janet M Wenzlau including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 31
Citations 1176
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Davidson H, Wenzlau J, OBrien R
Trends Endocrinol Metab . 2014 Apr; 25(8):415-24. PMID: 24751356
Human pancreatic β cells have exceptionally high zinc content. In β cells the highest zinc concentration is in insulin secretory granules, from which it is cosecreted with the hormone. Uptake...
12.
Asanghanwa M, Gorus F, Weets I, der Auwera B, Aminkeng F, Mbunwe E, et al.
Diabetes Res Clin Pract . 2013 Dec; 103(1):97-105. PMID: 24332797
Aims: We investigated the prevalence of diabetes autoantibodies (Abs) in Cameroonian patients and controls, assessed their contribution in disease classification and compared results with data from Belgium. Methods: Abs against...
13.
Wenzlau J, Hutton J
Curr Diab Rep . 2013 Aug; 13(5):608-15. PMID: 23900975
Autoantibodies are currently the most robust biomarkers of type 1 diabetes and are frequently used to establish entry criteria for the participation of genetically at-risk individuals in secondary prevention/intervention clinical...
14.
Yu L, Dong F, Miao D, Fouts A, Wenzlau J, Steck A
Diabetes Care . 2013 Feb; 36(8):2266-70. PMID: 23423694
Objective: We evaluated a novel electrochemiluminescent assay for insulin/proinsulin autoantibodies (ECL-IAA) as a new marker of the onset of islet autoimmunity and as a predictor of type 1 diabetes. Research...
15.
Mbunwe E, Van der Auwera B, Vermeulen I, Demeester S, Van Dalem A, Balti E, et al.
Diabetes . 2012 Nov; 62(4):1345-50. PMID: 23160529
We investigated whether HLA-A*24 typing complements screening for HLA-DQ and for antibodies (Abs) against insulin, GAD, IA-2 (IA-2A), and zinc transporter-8 (ZnT8A) for prediction of rapid progression to type 1...
16.
Burbelo P, Lebovitz E, Bren K, Bayat A, Paviol S, Wenzlau J, et al.
PLoS One . 2012 Oct; 7(9):e45216. PMID: 23028856
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody...
17.
Yu L, Boulware D, Beam C, Hutton J, Wenzlau J, Greenbaum C, et al.
Diabetes Care . 2012 Mar; 35(6):1213-8. PMID: 22446173
Objective: We assessed diabetes risk associated with zinc transporter-8 antibodies (ZnT8A), islet cell antibodies (ICA), and HLA type and age in relatives of people with type 1 diabetes with the...
18.
Wenzlau J, Frisch L, Hutton J, Davidson H
Diabetes Metab Res Rev . 2011 Nov; 27(8):883-6. PMID: 22069278
Background: Identification of the major humoral epitopes in zinc transporter 8 (ZnT8) will expand the range of biomarkers for human type 1 diabetes and may provide clues to the mechanisms...
19.
Lampasona V, Schlosser M, Mueller P, Williams A, Wenzlau J, Hutton J, et al.
Clin Chem . 2011 Oct; 57(12):1693-702. PMID: 21980171
Background: Zinc transporter 8 (ZnT8) is a recently identified major autoantigen in type 1 diabetes, and autoantibodies to ZnT8 (ZnT8A) are new markers for disease prediction and diagnosis. Here we...
20.
Vermeulen I, Weets I, Asanghanwa M, Ruige J, Van Gaal L, Mathieu C, et al.
Diabetes Care . 2011 Jul; 34(8):1760-5. PMID: 21715527
Objective: We investigated whether measuring autoantibodies against zinc transporter 8 (ZnT8A) and IA-2β (IA-2βA) may improve classification of new-onset type 1 diabetic patients based on detection of autoantibodies against insulin...