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Janet L Crane

Explore the profile of Janet L Crane including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1935
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Recent Articles
1.
Sadlowski A, See J, Bharill S, Zhang W, Otte A, Loscalzo E, et al.
J Bone Miner Res . 2025 Mar; PMID: 40080633
In murine models, glucocorticoids decrease preosteoclast (POC) platelet-derived growth factor type BB (PDGF-BB), reducing migration of endothelial precursor and osteoprogenitor cells, impairing skeletal angiogenesis and osteogenesis. To explore translation to...
2.
Shindo S, Nakamura S, Rawas-Qalaji M, Heidari A, Pastore M, Okamoto M, et al.
bioRxiv . 2024 Sep; PMID: 39282284
Significance Statement: The mechanosensitive Ca channel Piezo1 plays important regulatory roles in a variety of cellular activities. RANKL-mediated OC-genesis requires permissive co-stimulatory signal from ITAM receptors, such as OSCAR and...
3.
Vanderniet J, Szymczuk V, Hogler W, Beck-Nielsen S, Uday S, Merchant N, et al.
J Clin Endocrinol Metab . 2023 Dec; 109(5):1371-1382. PMID: 38041865
Context: Denosumab is an effective treatment for many receptor activator of nuclear factor kappa-B ligand (RANKL)-mediated disorders but there are potential safety considerations and limited data to guide its use...
4.
Loscalzo E, See J, Bharill S, Yousefzadeh N, Gough E, Wu M, et al.
Osteoporos Int . 2023 Oct; 35(2):327-338. PMID: 37872346
Purpose: Glucocorticoids prolong ambulation in boys with Duchenne muscular dystrophy; however, they have significant endocrine side effects. We assessed the impact of growth hormone (GH), testosterone, and/or zoledronic acid (ZA)...
5.
Kang M, Wu M, Crane J
Bone . 2023 Apr; 172:116778. PMID: 37088336
Tissue non-specific alkaline phosphatase (TNSALP) is an enzyme that is tethered to the cell membrane by glycosylphosphatidylinositol (GPI) and converts inorganic pyrophosphate to inorganic phosphate. Inorganic phosphate combines with calcium...
6.
McDaniel C, Adams D, Steele K, Hammill A, Merrow A, Crane J, et al.
Pediatr Blood Cancer . 2023 Jan; 70(4):e30219. PMID: 36683202
Kaposiform lymphangiomatosis (KLA) is a life-threatening rare disease that can cause substantial morbidity, mortality, and social burdens for patients and their families. Diagnosis often occurs long after initial symptoms, and...
7.
Crane J, Misra M
Front Endocrinol (Lausanne) . 2021 Jul; 12:725655. PMID: 34290674
No abstract available.
8.
Ferriero K, Shah B, Yan Y, Khatri S, Caccamese J, Napoli J, et al.
Front Pediatr . 2020 Oct; 8:515. PMID: 33042901
Noonan syndrome is a genetic disorder caused by mutations in the RAS/MAPK pathway. Multiple giant cell lesions are a rare sequelae of disruptions in this pathway, termed Noonan-like multiple giant...
9.
Daneshdoost S, El Abiad J, Ruble K, Jones L, Crane J, Morris C, et al.
J Pediatr Hematol Oncol . 2020 Apr; 43(3):e365-e370. PMID: 32324697
Background: Despite improved outcomes in children with leukemia, complications such as osteonecrosis are common. We conducted a systematic review to investigate the role of bisphosphonates in reducing pain, improving mobility,...
10.
Hu B, Lv X, Chen H, Xue P, Gao B, Wang X, et al.
J Clin Invest . 2020 Mar; 130(7):3483-3498. PMID: 32191640
The sensory nerve was recently identified as being involved in regulation of bone mass accrual. We previously discovered that prostaglandin E2 (PGE2) secreted by osteoblasts could activate sensory nerve EP4...