Janet Arras
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Explore the profile of Janet Arras including associated specialties, affiliations and a list of published articles.
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10
Citations
134
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Recent Articles
1.
Arras J, Calderon-Diaz A, Lebedkin S, Gozem S, McMillen C, Bhuvanesh N, et al.
Inorg Chem
. 2024 Jun;
63(28):12943-12957.
PMID: 38935842
Defined arrays of transition metal ions embedded in tailored polydentate ligand scaffolds allow for a systematic design of their physical properties. Such molecular strings of closed-shell transition metal centers are...
2.
Arras J, Ugarte Trejo O, Bhuvanesh N, Stollenz M
Chem Commun (Camb)
. 2022 Jan;
58(9):1418-1421.
PMID: 35001099
A bis(amidine) ligand operates as a molecular lock for two AuMes fragments. The resulting complex retains a flexible double macrocycle with two non-conventional N-H⋯C hydrogen bonds and distinct intramolecular dispersion...
3.
Arras J, Thomas K, Myers P, Cross A, Osei A, Vazquez G, et al.
Am J Cancer Res
. 2021 Nov;
11(10):4768-4787.
PMID: 34765292
Triple-Negative Breast Cancers (TNBCs) constitute roughly 10-20% of breast cancers and are associated with poor clinical outcomes. Previous work from our laboratory and others has determined that the cytoplasmic adaptor...
4.
ODea C, Ugarte Trejo O, Arras J, Ehnbom A, Bhuvanesh N, Stollenz M
J Org Chem
. 2019 Sep;
84(21):14217-14226.
PMID: 31560534
Hexadentate bis(amidines) form versatile networks of hydrogen bonds both in solid state and solution, as revealed by X-ray crystallography, IR, and NMR spectroscopy. Moreover, the corresponding bis(amidinates) produce blue and...
5.
Arras J, Kruczynski T, Bresien J, Schulz A, Schnockel H
Angew Chem Int Ed Engl
. 2018 Nov;
58(3):716-721.
PMID: 30408338
Magnesium(I) halides (Mg X; X=Cl, Br, I), as high temperature molecules, are trapped and finally stored at -80 °C in toluene/donor solutions. These solutions provide insights into the fundamental mechanism...
6.
Wang L, Arras J, Katsha A, Hamdan S, Belkhiri A, Ecsedy J, et al.
Mol Oncol
. 2017 Apr;
11(8):981-995.
PMID: 28417568
De novo and acquired resistance to platinum therapy such as cisplatin (CDDP) is a clinical challenge in gastric cancer treatment. Aberrant expression and activation of aurora kinase A (AURKA) and...
7.
Katsha A, Wang L, Arras J, Omar O, Ecsedy J, Belkhiri A, et al.
Clin Cancer Res
. 2017 Jan;
23(14):3756-3768.
PMID: 28073841
Aurora kinase A (AURKA) is overexpressed in several cancer types, making it an attractive druggable target in clinical trials. In this study, we investigated the role of AURKA in regulating...
8.
Arras J, Eichele K, Maryasin B, Schubert H, Ochsenfeld C, Wesemann L
Inorg Chem
. 2016 Apr;
55(9):4669-75.
PMID: 27071033
A bivalent tin complex [Sn(NP)2] (NP = [(2-Me2NC6H4)P(C6H5)](-)) was prepared and characterized by X-ray diffraction and solution and solid-state nuclear magnetic resonance (NMR) spectroscopy. In agreement with the X-ray structures...
9.
Katsha A, Arras J, Soutto M, Belkhiri A, El-Rifai W
Mol Oncol
. 2014 Jun;
8(8):1419-28.
PMID: 24953013
Aurora kinase A is a frequently amplified and overexpressed gene in upper gastrointestinal adenocarcinomas (UGCs). Using in vitro cell models of UGCs, we investigated whether AURKA can regulate Signal Transducer...
10.
Sehdev V, Katsha A, Arras J, Peng D, Soutto M, Ecsedy J, et al.
Clin Cancer Res
. 2013 Nov;
20(1):76-86.
PMID: 24240108
Purpose: Suppression of P53 (tumor protein 53) transcriptional function mediates poor therapeutic response in patients with cancer. Aurora kinase A (AURKA) and human double minute 2 (HDM2) are negative regulators...