Janell M Schelter
Overview
Explore the profile of Janell M Schelter including associated specialties, affiliations and a list of published articles.
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8
Citations
3095
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Recent Articles
1.
Dey J, Ditzler S, Knoblaugh S, Hatton B, Schelter J, Cleary M, et al.
Mol Cell Biol
. 2012 Aug;
32(20):4104-15.
PMID: 22869526
Deregulated developmental processes in the cerebellum cause medulloblastoma, the most common pediatric brain malignancy. About 25 to 30% of cases are caused by mutations increasing the activity of the Sonic...
2.
Sundaram P, Hultine S, Smith L, Dews M, Fox J, Biyashev D, et al.
Cancer Res
. 2011 Oct;
71(24):7490-501.
PMID: 22028325
Thrombospondin-1 (TSP-1) is an endogenous inhibitor of angiogenesis encoded by the THBS1 gene, whose promoter is activated by p53. In advanced colorectal cancers (CRC), its expression is sustained or even...
3.
Dews M, Fox J, Hultine S, Sundaram P, Wang W, Liu Y, et al.
Cancer Res
. 2010 Oct;
70(20):8233-46.
PMID: 20940405
c-Myc stimulates angiogenesis in tumors through mechanisms that remain incompletely understood. Recent work indicates that c-Myc upregulates the miR-17∼92 microRNA cluster and downregulates the angiogenesis inhibitor thrombospondin-1, along with other...
4.
Georges S, Biery M, Kim S, Schelter J, Guo J, Chang A, et al.
Cancer Res
. 2008 Dec;
68(24):10105-12.
PMID: 19074876
Cell cycle arrest in response to DNA damage is an important antitumorigenic mechanism. MicroRNAs (miRNAs) were recently shown to play key regulatory roles in cell cycle progression. For example, miR-34a...
5.
Chung E, Dews M, Cozma D, Yu D, Wentzel E, Chang T, et al.
Cancer Biol Ther
. 2008 Aug;
7(11):1758-64.
PMID: 18708755
The dleu2 tumor suppressor locus encodes two microRNAs, miR-15a and miR-16, which are thought to play an important role in B-cell neoplasms. However, relatively little is known about proteins that...
6.
Ivanovska I, Ball A, Diaz R, Magnus J, Kibukawa M, Schelter J, et al.
Mol Cell Biol
. 2008 Jan;
28(7):2167-74.
PMID: 18212054
microRNAs in the miR-106b family are overexpressed in multiple tumor types and are correlated with the expression of genes that regulate the cell cycle. Consistent with these observations, miR-106b family...
7.
Lim L, Lau N, Garrett-Engele P, Grimson A, Schelter J, Castle J, et al.
Nature
. 2005 Feb;
433(7027):769-73.
PMID: 15685193
MicroRNAs (miRNAs) are a class of noncoding RNAs that post-transcriptionally regulate gene expression in plants and animals. To investigate the influence of miRNAs on transcript levels, we transfected miRNAs into...
8.
Mao M, Biery M, Kobayashi S, Ward T, Schimmack G, Burchard J, et al.
Genomics
. 2004 Jun;
83(6):989-99.
PMID: 15177553
High-capacity methods for assessing gene function have become increasingly important because of the increasing number of newly identified genes emerging from large-scale genome sequencing and cDNA cloning efforts. We investigated...