Jane Y Wu
Overview
Explore the profile of Jane Y Wu including associated specialties, affiliations and a list of published articles.
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104
Citations
3754
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Recent Articles
1.
Yuasa-Kawada J, Kinoshita-Kawada M, Hiramoto M, Yamagishi S, Mishima T, Yasunaga S, et al.
Neural Regen Res
. 2025 Feb;
PMID: 39995079
The nervous system processes a vast amount of information, performing computations that underlie perception, cognition, and behavior. During development, neuronal guidance genes, which encode extracellular cues, their receptors, and downstream...
2.
Zhang W, Li Y, Fung A, Li Z, Jang H, Zha H, et al.
Nat Commun
. 2024 Feb;
15(1):1599.
PMID: 38383552
Lipids play crucial roles in many biological processes. Mapping spatial distributions and examining the metabolic dynamics of different lipid subtypes in cells and tissues are critical to better understanding their...
3.
Ma J, Liu L, Song L, Liu J, Yang L, Chen Q, et al.
Cell Death Dis
. 2023 Nov;
14(11):735.
PMID: 37951930
Though TDP-43 protein can be translocated into mitochondria and causes mitochondrial damage in TDP-43 proteinopathy, little is known about how TDP-43 is imported into mitochondria. In addition, whether mitochondrial damage...
4.
Li Y, Chang P, Sankaran S, Jang H, Nie Y, Zeng A, et al.
GEN Biotechnol
. 2023 Jun;
2(3):247-261.
PMID: 37363411
Studies have shown that brain lipid metabolism is associated with biological aging and influenced by dietary and genetic manipulations; however, the underlying mechanisms are elusive. High-resolution imaging techniques propose a...
5.
Yuasa-Kawada J, Kinoshita-Kawada M, Tsuboi Y, Wu J
Protein Cell
. 2023 Mar;
14(4):238-261.
PMID: 36942388
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to their synaptic targets by sensing various extracellular cues in spatiotemporally controlled manners. These evolutionally conserved guidance cues...
6.
Jang H, Li Y, Fung A, Bagheri P, Hoang K, Skowronska-Krawczyk D, et al.
Nat Methods
. 2023 Feb;
20(3):448-458.
PMID: 36797410
Stimulated Raman scattering (SRS) offers the ability to image metabolic dynamics with high signal-to-noise ratio. However, its spatial resolution is limited by the numerical aperture of the imaging objective and...
7.
Ma J, Wu J, Zhu L
Bioinformatics
. 2022 Aug;
38(19):4474-4480.
PMID: 35946527
Motivation: Alternative splicing is an important mechanism to generate transcriptomic and phenotypic diversity. Existing methods have limited power to detect orthologous isoforms. Results: We develop a new method, EGIO, to...
8.
Li Y, Bagheri P, Chang P, Zeng A, Hao J, Fung A, et al.
Front Aging
. 2022 Jul;
2:819903.
PMID: 35822015
Emerging studies have shown that lipids and proteins play versatile roles in various aspects of aging. High-resolution optical imaging provides a powerful approach to study the metabolic dynamics of lipids...
9.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, et al.
EMBO Rep
. 2021 Jun;
22(7):e52006.
PMID: 34096155
Tunneling nanotubes (TNTs) are actin-rich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs transport signaling molecules, vesicles, organelles, and even pathogens. However,...
10.
Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, et al.
Bio Protoc
. 2021 Mar;
9(18):e3373.
PMID: 33654869
Developing axons change responsiveness to guidance cues during the journey to synapse with target cells. Axon crossing at the ventral midline serves as a model for studying how axons accomplish...