Jane M Glick
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Explore the profile of Jane M Glick including associated specialties, affiliations and a list of published articles.
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18
Citations
834
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Recent Articles
1.
Zhang Y, McGillicuddy F, Hinkle C, ONeill S, Glick J, Rothblat G, et al.
Circulation
. 2010 Mar;
121(11):1347-55.
PMID: 20212278
Background: Adipose harbors a large depot of free cholesterol. However, a role for adipose in cholesterol lipidation of high-density lipoprotein (HDL) in vivo is not established. We present the first...
2.
Griffon N, Jin W, Petty T, Millar J, Badellino K, Saven J, et al.
J Biol Chem
. 2009 Jul;
284(35):23322-30.
PMID: 19567873
Endothelial lipase (EL) is a member of a subfamily of lipases that act on triglycerides and phospholipids in plasma lipoproteins, which also includes lipoprotein lipase and hepatic lipase. EL has...
3.
Jin W, Wang X, Millar J, Quertermous T, Rothblat G, Glick J, et al.
Cell Metab
. 2007 Aug;
6(2):129-36.
PMID: 17681148
The risk of atherosclerosis is inversely associated with plasma levels of high-density lipoprotein cholesterol (HDL-C). However, HDL metabolism is incompletely understood, and there are few effective approaches to modulate HDL-C...
4.
Griffon N, Budreck E, Long C, Broedl U, Marchadier D, Glick J, et al.
J Lipid Res
. 2006 May;
47(8):1803-11.
PMID: 16682746
The triglyceride (TG) lipase gene subfamily, consisting of LPL, HL, and endothelial lipase (EL), plays a central role in plasma lipoprotein metabolism. Compared with LPL and HL, EL is relatively...
5.
Jin W, Fuki I, Seidah N, Benjannet S, Glick J, Rader D
J Biol Chem
. 2005 Aug;
280(44):36551-9.
PMID: 16109723
Plasma lipoprotein metabolism is tightly regulated by several members of the triglyceride lipase family, including endothelial lipase (EL) and lipoprotein lipase (LPL). Our previous work suggested that EL is proteolytically...
6.
Broedl U, Jin W, Fuki I, Glick J, Rader D
FASEB J
. 2004 Oct;
18(15):1891-3.
PMID: 15456739
Lipoprotein lipase (LPL) and endothelial lipase (EL), the most closely related enzymes among the members of the triglyceride lipase gene family with regard to primary sequence, have distinct lipolytic properties...
7.
Miller G, Long C, Bojilova E, Marchadier D, Badellino K, Blanchard N, et al.
J Lipid Res
. 2004 Sep;
45(11):2080-7.
PMID: 15342690
Human endothelial lipase (EL), a member of the triglyceride lipase gene family, has five potential N-linked glycosylation sites, two of which are conserved in both lipoprotein lipase and hepatic lipase....
8.
Broedl U, Maugeais C, Millar J, Jin W, Moore R, Fuki I, et al.
Circ Res
. 2004 May;
94(12):1554-61.
PMID: 15117821
Endothelial lipase (EL) has been found to be a key enzyme in high-density lipoprotein (HDL) metabolism in mice, leading to the concept that inhibition of EL could be a novel...
9.
Yancey P, Kawashiri M, Moore R, Glick J, Williams D, Connelly M, et al.
J Lipid Res
. 2003 Nov;
45(2):337-46.
PMID: 14594995
The effects of in vivo modulation of HDL phospholipid (PL) on scavenger receptor class BI (SR-BI)- and ATP binding cassette transporter 1 (ABCA1)-mediated efflux were examined by overexpressing either endothelial...
10.
Maugeais C, Tietge U, Broedl U, Marchadier D, Cain W, McCoy M, et al.
Circulation
. 2003 Oct;
108(17):2121-6.
PMID: 14517167
Background: Factors that regulate the metabolism of HDL and apolipoprotein A-I (apoA-I) are incompletely understood. Overexpression of endothelial lipase (EL) markedly reduces plasma levels of HDL cholesterol and apoA-I in...