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Jane A Mitchell

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Articles 144
Citations 3569
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Recent Articles
1.
Alsulayyim A, Alasmari A, Price L, McCabe C, Alghamdi S, Philip K, et al.
Thorax . 2025 Feb; PMID: 39922710
Dietary nitrate supplementation, which improves skeletal muscle oxygen utilisation, vascular endothelial function and exercise capacity in people with chronic obstructive pulmonary disease, may benefit other lung conditions. In a double-blind,...
2.
Vaja R, Ferreira P, Portas L, Ahmetaj-Shala B, Cypaite N, Gashaw H, et al.
Eur Heart J Open . 2024 Dec; 4(6):oeae088. PMID: 39660078
Aims: The Standard care vs. Celecoxib Outcome Trial (SCOT) found similar risk of cardiovascular events with traditional non-steroidal anti-inflammatory drugs (NSAIDs) and the cyclooxygenase-2-selective drug celecoxib. While pre-clinical work has...
3.
Reddy S, Newman J, Leavy O, Ghani H, Pepke-Zaba J, Cannon J, et al.
Eur Respir J . 2024 Jul; 64(2. PMID: 39060016
Background: Pulmonary embolism (PE) is a well-recognised complication of coronavirus disease 2019 (COVID-19) infection, and chronic thromboembolic pulmonary disease with and without pulmonary hypertension (CTEPD/CTEPH) are potential life-limiting consequences. At...
4.
Ahmetaj-Shala B, Olanipekun M, Tesfai A, MacCallum N, Kirkby N, Quinlan G, et al.
Sci Rep . 2024 May; 14(1):11800. PMID: 38782945
No abstract available.
5.
Vaja R, Lopes-Pires M, Shala F, Cypaite N, Vinokurova M, Ferreira P, et al.
J Thromb Haemost . 2024 Mar; 22(6):1798-1801. PMID: 38518895
No abstract available.
6.
Alasmari A, Alsulayyim A, Alghamdi S, Philip K, Buttery S, Banya W, et al.
Eur Respir J . 2023 Dec; 63(2). PMID: 38123239
Background: Short-term studies suggest that dietary nitrate (NO ) supplementation may improve the cardiovascular risk profile, lowering blood pressure (BP) and enhancing endothelial function. It is not clear if these...
7.
Judina A, Niglas M, Leonov V, Kirkby N, Diakonov I, Wright P, et al.
Cells . 2023 Dec; 12(23). PMID: 38067192
(1) Pulmonary hypertension (PH)-associated right ventricular (RV) failure is linked to a reduction in pulmonary vasodilators. Treprostinil has shown effectiveness in PAH patients with cardiac decompensation, hinting at potential cardiac...
8.
Vinokurova M, Lopes-Pires M, Cypaite N, Shala F, Armstrong P, Ahmetaj-Shala B, et al.
Arterioscler Thromb Vasc Biol . 2023 Oct; 44(1):271-286. PMID: 37823267
Background: Prostacyclin is a fundamental signaling pathway traditionally associated with the cardiovascular system and protection against thrombosis but which also has regulatory functions in fibrosis, proliferation, and immunity. Prevailing dogma...
9.
May J, Mitchell J, Gisli Jenkins R
J Clin Invest . 2023 Sep; 133(18). PMID: 37712420
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor survival. The incidence and mortality of IPF are rising, but treatment remains limited. Currently, two drugs...
10.
Ferreira P, Vaja R, Lopes-Pires M, Crescente M, Yu H, Nusing R, et al.
Kidney Int Rep . 2023 Jun; 8(6):1231-1238. PMID: 37284684
Introduction: Through the production of prostacyclin, cyclooxygenase (COX)-2 protects the cardiorenal system. Asymmetric dimethylarginine (ADMA), is a biomarker of cardiovascular and renal disease. Here we determined the relationship between COX-2/prostacyclin,...