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Jana Keil

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Articles 19
Citations 209
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Recent Articles
1.
Meyer G, Siemes A, Kuhne J, Bevzenko I, Baszczok V, Keil J, et al.
Eur J Immunol . 2025 Feb; 55(2):e202451266. PMID: 39931744
The immunosuppressed state of transplant patients allows opportunistic pathogens such as human cytomegalovirus (HCMV) to cause severe disease. Therefore, inducing and boosting immunity against HCMV in recipients prior to organ...
2.
Chichelnitskiy E, Goldschmidt I, Ruhl L, Rubsamen N, Jaeger V, Karch A, et al.
J Hepatol . 2024 May; 81(5):862-871. PMID: 38821361
Background & Aims: After pediatric liver transplantation (pLT), children undergo life-long immunosuppression since reliable biomarkers for the assessment of rejection probability are scarce. In the multicenter (n = 7) prospective...
3.
Ludwig K, Chichelnitskiy E, Kuhne J, Wiegmann B, Iske J, Ledwoch N, et al.
Front Immunol . 2023 Nov; 14:1257526. PMID: 37936714
Introduction: Following heart transplantation, a cascade of immunological responses is initiated influencing the clinical outcome and long-term survival of the transplanted patients. The anti-inflammatory cytokine interleukin-10 (IL-10) was shown to...
4.
Radomsky L, Koch A, Olbertz C, Liu Y, Beushausen K, Keil J, et al.
Front Cardiovasc Med . 2023 Oct; 10:1245618. PMID: 37808880
Background: lung perfusion (EVLP) uses continuous normothermic perfusion to reduce ischemic damage and to improve post-transplant outcomes, specifically for marginal donor lungs after the donation after circulatory death. Despite major...
5.
Qu D, Preuss V, Hagemeier L, Radomsky L, Beushausen K, Keil J, et al.
Pediatr Res . 2023 Sep; 95(4):949-958. PMID: 37679518
Background: Sudden infant death syndrome (SIDS) has been considered to be triggered by a combination of underlying immune dysregulation and infections. The thymus is a crucial lymphatic organ responsible for...
6.
Iske J, Wiegmann B, Ius F, Chichelnitskiy E, Ludwig K, Kuhne J, et al.
Eur J Immunol . 2023 Apr; 53(7):e2250097. PMID: 37119053
Early kinetics of lymphocyte subsets involved in tolerance and rejection following heart transplantation (HTx) are barely defined. Here, we aimed to delineate the early alloimmune response immediately after HTx. Therefore,...
7.
Ruhl L, Kuhne J, Beushausen K, Keil J, Christoph S, Sauer J, et al.
Front Immunol . 2023 Apr; 14:1120010. PMID: 37033958
Introduction: SARS-CoV-2 vaccination is the leading strategy to prevent severe courses after SARS-CoV-2 infection. In our study, we analyzed humoral and cellular immune responses in detail to three consecutive homologous...
8.
Qu D, Engelmann T, Preuss V, Hagemeier L, Radomsky L, Beushausen K, et al.
Pediatr Res . 2022 Aug; 93(5):1239-1249. PMID: 35986144
Background: For sudden infant death syndrome (SIDS), an impaired immunocompetence has been discussed for a long time. Cytokines and chemokines are soluble immune mediators (SIM) whose balance is essential for...
9.
Hitz A, Blasing K, Wiegmann B, Bellmas-Sanz R, Chichelnitskiy E, Wandrer F, et al.
Front Immunol . 2021 Dec; 12:778885. PMID: 34966390
Introduction: For end-stage lung diseases, double lung transplantation (DLTx) is the ultimate curative treatment option. However, acute and chronic rejection and chronic dysfunction are major limitations in thoracic transplantation medicine....
10.
Ruhl L, Pink I, Kuhne J, Beushausen K, Keil J, Christoph S, et al.
Signal Transduct Target Ther . 2021 Dec; 6(1):418. PMID: 34893580
The systemic processes involved in the manifestation of life-threatening COVID-19 and in disease recovery are still incompletely understood, despite investigations focusing on the dysregulation of immune responses after SARS-CoV-2 infection....