Jana Keil
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Explore the profile of Jana Keil including associated specialties, affiliations and a list of published articles.
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19
Citations
209
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Recent Articles
11.
Ledwoch N, Wiegmann B, Chichelnitskiy E, Wandrer F, Kuhne J, Beushausen K, et al.
Cytokine
. 2021 Oct;
149:155744.
PMID: 34649160
Background: Ischemia/reperfusion injury (IRI) is associated with inflammatory responses contributing to the development of primary graft dysfunction (PGD) and rejection. Here, we investigated the pathophysiology of IRI and the early...
12.
Kuhne J, Neudorfl C, Beushausen K, Keil J, Malysheva S, Wandrer F, et al.
Transpl Immunol
. 2020 Apr;
61:101291.
PMID: 32330566
Belatacept, Nulojix®, inhibits the interaction of CD28 on naïve T cells with B7.1/B7.2 (CD80/86) on antigen presenting cells, leading to T cell hyporesponsiveness and anergy and is approved as immunosuppressive...
13.
Warnecke A, Prenzler N, Schmitt H, Daemen K, Keil J, Dursin M, et al.
Front Neurol
. 2019 Jul;
10:665.
PMID: 31293504
The molecular pathomechanisms in the majority of patients suffering from acute or progressive sensorineural hearing loss cannot be determined yet. The size and the complex architecture of the cochlea make...
14.
Egelkamp J, Chichelnitskiy E, Kuhne J, Wandrer F, Daemen K, Keil J, et al.
Am J Transplant
. 2019 May;
19(10):2692-2704.
PMID: 31062482
The role of endothelial cells in the pathophysiology of antibody-mediated rejection after renal transplantation has been widely investigated. We expand this scenario to the impact of epithelial cells on the...
15.
Przybylek B, Boethig D, Neumann A, Borchert-Moerlins B, Daemen K, Keil J, et al.
Am J Cardiol
. 2019 Jan;
123(7):1114-1119.
PMID: 30660351
To date, there are no established noninvasive biomarkers available for prediction of cardiac allograft vasculopathy (CAV) after orthotopic heart transplantation (OHT). Inflammatory processes are supposed to play a central role...
16.
Goldschmidt I, Karch A, Mikolajczyk R, Mutschler F, Junge N, Pfister E, et al.
BMC Gastroenterol
. 2018 May;
18(1):63.
PMID: 29769027
Background: Although trough levels of immunosuppressive drugs are largely used to monitor immunosuppressive therapy after solid organ transplantation, there is still no established tool that allows for a validated assessment...
17.
Hoffmann U, Neudorfl C, Daemen K, Keil J, Stevanovic-Meyer M, Lehner F, et al.
PLoS One
. 2015 Jul;
10(7):e0132484.
PMID: 26147651
To explore phenotype and function of NK cells in kidney transplant recipients, we investigated the peripheral NK cell repertoire, capacity to respond to various stimuli and impact of immunosuppressive drugs...
18.
Neudoerfl C, Mueller B, Blume C, Daemen K, Stevanovic-Meyer M, Keil J, et al.
Front Immunol
. 2013 Mar;
4:46.
PMID: 23450662
In the context of kidney transplantation, little is known about the involvement of natural killer (NK) cells in the immune reaction leading to either rejection or immunological tolerance under immunosuppression....
19.
Nazarenko I, Jenny M, Keil J, Gieseler C, Weisshaupt K, Sehouli J, et al.
Mol Cancer Res
. 2010 May;
8(6):919-34.
PMID: 20501645
Intracellular signaling governed by serine/threonine kinases comprises the molecular interface between cell surface receptors and the nuclear transcriptional machinery. The protein kinase C (PKC) family members are involved in the...
20.
Bluthgen N, Legewie S, Kielbasa S, Schramme A, Tchernitsa O, Keil J, et al.
FEBS J
. 2009 Jan;
276(4):1024-35.
PMID: 19154344
Mitogen-activated protein kinase (MAPK) signaling determines crucial cell fate decisions in most cell types, and mediates cellular transformation in many types of cancer. The activity of MAPK is controlled by...