Jana Gerstmeier
Overview
Explore the profile of Jana Gerstmeier including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
754
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Recent Articles
1.
Pace S, Meyer K, Troisi F, Bilancia R, DAvino D, Parisi O, et al.
FASEB J
. 2024 Jul;
38(14):e23828.
PMID: 39037419
Unresolved inflammation, due to unfavorable imbalances between pro-inflammatory and pro-resolving mediators, leads to chronic inflammatory pathologies that are often sex-biased and regulated by sex hormones, including inflammatory bowel disease. Lipid...
2.
Werz O, Gerstmeier J, Libreros S, De La Rosa X, Werner M, Norris P, et al.
Nat Commun
. 2023 Sep;
14(1):6056.
PMID: 37770436
No abstract available.
3.
Rao Z, Brunner E, Giszas B, Iyer-Bierhoff A, Gerstmeier J, Borner F, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(35):e2302070120.
PMID: 37603745
Glucocorticoids (GC) are potent anti-inflammatory agents, broadly used to treat acute and chronic inflammatory diseases, e.g., critically ill COVID-19 patients or patients with chronic inflammatory bowel diseases. GC not only...
4.
Jovicic E, Janez A, Eichmann T, Koren S, Brglez V, Jordan P, et al.
Mol Metab
. 2023 Aug;
76:101791.
PMID: 37586657
Objectives: Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids and precursors of oxygenated lipid mediators with diverse functions, including the control of cell growth, inflammation and tumourigenesis. However,...
5.
Borner F, Pace S, Jordan P, Gerstmeier J, Gomez M, Rossi A, et al.
Adv Sci (Weinh)
. 2022 Dec;
10(6):e2205604.
PMID: 36567268
Specialized pro-resolving mediators (SPM), primarily produced in innate immune cells, exert crucial bioactions for resolving inflammation. Among various lipoxygenases (LOX), 15-LOX-1 is key for SPM biosynthesis, but cellular activation principles...
6.
Napagoda M, Gerstmeier J, Butschek H, Lorenz S, De Soyza S, Qader M, et al.
Pharmaceuticals (Basel)
. 2022 Apr;
15(4).
PMID: 35455433
Benth is used in Sri Lankan folk medicine as a remedy for inflammatory conditions and microbial infections. Our previous investigations revealed potent 5-lipoxygenase (5-LO) inhibitory activity in lipophilic extracts of...
7.
Miek L, Jordan P, Gunther K, Pace S, Beyer T, Kowalak D, et al.
Immunology
. 2022 Feb;
166(1):47-67.
PMID: 35143048
Staphylococcus aureus causes severe infections associated with inflammation, such as sepsis or osteomyelitis. Inflammatory processes are regulated by distinct lipid mediators (LMs) but how their biosynthetic pathways are orchestrated in...
8.
Hoff J, Karl B, Gerstmeier J, Beekmann U, Schmolz L, Borner F, et al.
Nanomaterials (Basel)
. 2021 Aug;
11(8).
PMID: 34443772
Inflammation is a hallmark of tissue remodeling during wound healing. The inflammatory response to wounds is tightly controlled and well-coordinated; dysregulation compromises wound healing and causes persistent inflammation. Topical application...
9.
Andreas N, Muller S, Templin N, Jordan P, Schuhwerk H, Muller M, et al.
Arthritis Res Ther
. 2021 Aug;
23(1):222.
PMID: 34429153
Background: The incidence of rheumatoid arthritis is correlated with age. In this study, we analyzed the association of the incidence and severity of glucose-6-phosphate isomerase (G6PI)-induced arthritis with age in...
10.
Neukirch K, Alsabil K, Dinh C, Bilancia R, Raasch M, Ville A, et al.
J Med Chem
. 2021 Jul;
64(15):11496-11526.
PMID: 34279935
Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the systemic concentrations of resolvin E3, a specialized proresolving lipid mediator. SAR studies on...