Andreas Koeberle
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Explore the profile of Andreas Koeberle including associated specialties, affiliations and a list of published articles.
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118
Citations
1649
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Recent Articles
1.
Gollowitzer A, Pein H, Rao Z, Waltl L, Bereuter L, Loeser K, et al.
Nat Commun
. 2025 Feb;
16(1):1774.
PMID: 40000627
Cell death programs such as apoptosis and ferroptosis are associated with aberrant redox homeostasis linked to lipid metabolism and membrane function. Evidence for cross-talk between these programs is emerging. Here,...
2.
Koeberle S, Thurmer M, Su F, Werner M, Grander J, Hofer L, et al.
Theranostics
. 2025 Feb;
15(5):2006-2034.
PMID: 39897559
is used to protect against degenerative liver damage. The molecular mechanisms of its bioactive component, silybin, remained enigmatic, although membrane-stabilizing properties, modulation of membrane protein function, and metabolic regulation have...
3.
Plangger I, Muhlsteiger A, Berger J, Feilner J, Wurst K, Koeberle A, et al.
Chemistry
. 2024 Dec;
31(7):e202403811.
PMID: 39665294
We present a comprehensive account on the evolution of a synthetic platform for a subfamily of ent-pimaranes. For the most complex member, norflickinflimiod C, five distinct strategies relying on either...
4.
Neubauer C, Kragl M, Braun T, Filipek P, Bonyadi Rad E, Grander J, et al.
Eur J Dermatol
. 2024 Aug;
34(4):416-424.
PMID: 39193679
Atopic dermatitis (AD) is a highly prevalent chronic skin disease. Anti-inflammatory and antipruritic emollients (emollients plus) with excellent cosmetic properties may alleviate AD-related symptoms and reduce the number of exacerbations....
5.
Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkas K, Bindel N, et al.
Nat Cell Biol
. 2024 Jul;
26(9):1470-1481.
PMID: 39009641
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial-mesenchymal transition (EMT) programme. A mesenchymal phenotype predisposes to ferroptosis, a...
6.
Su F, Descher H, Bui-Hoang M, Stuppner H, Skvortsova I, Bonyadi Rad E, et al.
Redox Biol
. 2024 Jul;
75:103257.
PMID: 38955113
Ferroptosis, a lipid peroxidation-driven cell death program kept in check by glutathione peroxidase 4 and endogenous redox cycles, promises access to novel strategies for treating therapy-resistant cancers. Chlorido [N,N'-disalicylidene-1,2-phenylenediamine]iron (III)...
7.
Shamsudin N, Leong S, Koeberle A, Suriya U, Rungrotmongkol T, Chia S, et al.
Future Med Chem
. 2024 Jul;
16(15):1499-1517.
PMID: 38949858
Chromones are promising for anticancer drug development. 12 chromone-based compounds were synthesized and tested against cancer cell lines. Compound showed the highest cytotoxicity (LC 3.2 μM) against colorectal cancer cells,...
8.
Shkodra B, Kretzer C, Jordan P, Klemm P, Koeberle A, Pretzel D, et al.
J Nanobiotechnology
. 2024 Feb;
22(1):77.
PMID: 38408973
No abstract available.
9.
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans
Sharifi S, Chaudhari P, Martirosyan A, Eberhardt A, Witt F, Gollowitzer A, et al.
Nat Commun
. 2024 Feb;
15(1):1702.
PMID: 38402241
Ribosome biogenesis is initiated by RNA polymerase I (Pol I)-mediated synthesis of pre-ribosomal RNA (pre-rRNA). Pol I activity was previously linked to longevity, but the underlying mechanisms were not studied...
10.
Rullah K, Shamsudin N, Koeberle A, Tham C, Mohd Aluwi M, Leong S, et al.
Future Med Chem
. 2024 Jan;
16(1):75-99.
PMID: 38205612
Targeting lipopolysaccharide (LPS)/toll-like receptor 4 signaling in mononuclear phagocytes has been explored for the treatment of inflammation and inflammation-related disorders. However, only a few key targets have been translated into...