Jan Verhoeff
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Explore the profile of Jan Verhoeff including associated specialties, affiliations and a list of published articles.
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17
Citations
158
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Recent Articles
1.
Saris J, Bootsma S, Verhoeff J, Tuynman J, Wildenberg M, Rijnstra E, et al.
Front Immunol
. 2024 Jul;
15:1415457.
PMID: 39044825
Background: The occurrence of peritoneal metastasis (PM) in patients with colorectal cancer (CRC) has a dismal prognosis. There is often limited response to systemic- and immunotherapy, even in microsatellite unstable...
2.
Rodriguez E, Zwart E, Affandi A, Verhoeff J, de Kok M, Boyd L, et al.
Cancer Sci
. 2024 Apr;
115(7):2170-2183.
PMID: 38686549
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with a 5-year survival of less than 10%. More knowledge of the immune response developed in patients with PDAC is pivotal to...
3.
van Olst L, Kamermans A, Halters S, van der Pol S, Rodriguez E, Verberk I, et al.
Mol Neurodegener
. 2024 Apr;
19(1):38.
PMID: 38658964
Background: Alzheimer's disease (AD) is the most frequent cause of dementia. Recent evidence suggests the involvement of peripheral immune cells in the disease, but the underlying mechanisms remain unclear. Methods:...
4.
Verhoeff J, van Asten S, Kuijper L, van den Braber M, Amstalden-van Hove E, Haselberg R, et al.
N Biotechnol
. 2024 Mar;
81:33-42.
PMID: 38493996
We report the synthesis of a novel class of metal-complexing peptide-based polymers, which we name HyperMAPs (Hyper-loaded MetAl-complexed Polymers). The controlled solid-phase synthesis of HyperMAPs' scaffold peptide provides our polymer...
5.
Doeleman S, Reijnders T, Joosten S, Schuurman A, van Engelen T, Verhoeff J, et al.
J Infect
. 2024 Mar;
88(4):106131.
PMID: 38431153
Objectives: Lymphopenia at hospital admission occurs in over one-third of patients with community-acquired pneumonia (CAP), yet its clinical relevance and pathophysiological implications remain underexplored. We evaluated outcomes and immune features...
6.
Dusoswa S, Verhoeff J, van Asten S, Lubbers J, van den Braber M, Peters S, et al.
Front Immunol
. 2024 Feb;
15:1343484.
PMID: 38318180
Background: Glioblastomas manipulate the immune system both locally and systemically, yet, glioblastoma-associated changes in peripheral blood immune composition are poorly studied. Age and dexamethasone administration in glioblastoma patients have been...
7.
Reijnders T, Schuurman A, Verhoeff J, van den Braber M, Douma R, Faber D, et al.
Front Immunol
. 2023 Dec;
14:1260283.
PMID: 38077404
Background: Community-acquired pneumonia (CAP) represents a major health burden worldwide. Dysregulation of the immune response plays an important role in adverse outcomes in patients with CAP. Methods: We analyzed peripheral...
8.
Verhoeff J, Abeln S, Garcia-Vallejo J
BMC Bioinformatics
. 2022 Nov;
23(1):487.
PMID: 36384426
Background: Current methods of high-dimensional unsupervised clustering of mass cytometry data lack means to monitor and evaluate clustering results. Whether unsupervised clustering is correct is typically evaluated by agreement with...
9.
Elfiky A, Hageman I, Becker M, Verhoeff J, Li Yim A, Joustra V, et al.
Cells
. 2022 Sep;
11(18).
PMID: 36139421
Background: Myeloid cells are critical determinants of the sustained inflammation in Crohn's Disease (CD). Targeting such cells may be an effective therapeutic approach for refractory CD patients. Bromodomain and extra-terminal...
10.
de Krijger M, Hageman I, Li Yim A, Verhoeff J, Garcia Vallejo J, van Hamersveld P, et al.
Front Immunol
. 2022 Apr;
13:840935.
PMID: 35371111
Background: Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease affecting the intra- and extrahepatic bile ducts, and is strongly associated with ulcerative colitis (UC). In this study, we...