Ishtu L Hageman
Overview
Explore the profile of Ishtu L Hageman including associated specialties, affiliations and a list of published articles.
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6
Citations
39
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Recent Articles
1.
Joustra V, Li Yim A, de Bruyn J, Duijvestein M, Hageman I, de Jonge W, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142381
Prediction of endoscopic post-operative recurrence (POR) in Crohn's disease (CD) patients following ileocolonic resection (ICR) using clinical risk factors alone has thus far been inadequate. While peripheral blood leukocyte (PBL)...
2.
Elfiky A, Hageman I, Becker M, Verhoeff J, Li Yim A, Joustra V, et al.
Cells
. 2022 Sep;
11(18).
PMID: 36139421
Background: Myeloid cells are critical determinants of the sustained inflammation in Crohn's Disease (CD). Targeting such cells may be an effective therapeutic approach for refractory CD patients. Bromodomain and extra-terminal...
3.
Joustra V, Hageman I, Satsangi J, Adams A, Ventham N, de Jonge W, et al.
J Crohns Colitis
. 2022 Aug;
17(2):185-198.
PMID: 35998097
Background And Aims: Over the past decade, the DNA methylome has been increasingly studied in peripheral blood of inflammatory bowel disease [IBD] patients. However, a comprehensive summary and meta-analysis of...
4.
Ghiboub M, Koster J, Craggs P, Li Yim A, Shillings A, Hutchinson S, et al.
BMC Biol
. 2022 Aug;
20(1):182.
PMID: 35986286
Background: SP140 is a bromodomain-containing protein expressed predominantly in immune cells. Genetic polymorphisms and epigenetic modifications in the SP140 locus have been linked to Crohn's disease (CD), suggesting a role...
5.
de Krijger M, Hageman I, Li Yim A, Verhoeff J, Garcia Vallejo J, van Hamersveld P, et al.
Front Immunol
. 2022 Apr;
13:840935.
PMID: 35371111
Background: Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease affecting the intra- and extrahepatic bile ducts, and is strongly associated with ulcerative colitis (UC). In this study, we...
6.
Elfiky A, Ghiboub M, Li Yim A, Hageman I, Verhoeff J, de Krijger M, et al.
J Crohns Colitis
. 2021 Oct;
16(4):668-681.
PMID: 34633041
Background And Aims: Histone deacetylase inhibitors [HDACi] exert potent anti-inflammatory effects. Because of the ubiquitous expression of HDACs, clinical utility of HDACi is limited by off-target effects. Esterase-sensitive motif [ESM]...